Hyper Tet, HyperTET S/D (tetanus immune globulin (TIG)) dosing, indications, interactions, adverse effects, and more

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Sections tetanus immune globulin (TIG)
Dosing & Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology
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Patient Handout
Formulary

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

powder for injection

250 units

Tetanus

Prophylaxis: 250 Units IM (single dose)

Active tetanus: 3000-6000 Units IM

Clean minor wound

# doses unknown or 0-2 doses; toxoid only
>3 doses; toxoid if >10 years ago

All other wounds

# doses unknown or 0-1 doses; toxoid plus IG
2 doses; toxoid, but no IG if wound <24 hours old
>3 doses; toxoid if >5 years ago, and no IG

Dosage Forms & Strengths

powder for injection

250 units

Tetanus Prophylaxis

<7 years old: 4 Unit/kg or 250 Units IM

>7 years old: 250 Units IM (single dose)

Tetanus Treatment

3000-6000 Units IM

Interaction Checker

Enter a drug name and tetanus immune globulin (TIG)

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Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

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Frequency Not Defined

Urticaria

Injection site pain

N/V

Fever

Lethargy

Chest tightness

Anaphylaxis

Angioneurotic edema

Nephrotic syndrome (rare)

Contraindications

Hypersensitivity to gamma globulin, IgA, thimerosal

Cautions

Thrombocytopenia or coagulation disorders may contraindicate IM injection

Made from human plasma, small risk of viral transmission through administration

Pregnancy & Lactation

Pregnancy Category: C

Lactation: not known if excreted in breast milk, no adverse effects reported

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Mechanism of Action

Human immune globulins from donors

Pharmacokinetics

Half-life: 23 days

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Patient Handout

Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

View explanations for tiers and restrictions

Tier	Description
1	This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2	This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC	NOT COVERED – Drugs that are not covered by the plan.

Code	Definition
PA	Prior Authorization Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL	Quantity Limits Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST	Step Therapy Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR	Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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Sections tetanus immune globulin (TIG)
Dosing & Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology
Images
Patient Handout
Formulary

tetanus immune globulin (TIG) (Rx)

Dosing & Uses

Dosage Forms & Strengths

powder for injection

Tetanus

Clean minor wound

All other wounds

Dosage Forms & Strengths

powder for injection

Tetanus Prophylaxis

Tetanus Treatment

Interactions

Interaction Checker

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

Adverse Effects

Frequency Not Defined

Warnings

Contraindications

Cautions

Pregnancy & Lactation

Pregnancy Categories

Pharmacology

Mechanism of Action

Pharmacokinetics

Images

Patient Handout

Formulary

Plans

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