Dosing & Uses
Dosage Forms & Strengths
capsule
- 1mg
- 2mg
- 5mg
- 10mg
Benign Prostate Hyperplasia
Initial: 1 mg PO qHS
May gradually increase to 5 mg PO qHS; up to 20 mg/day beneficial for some
Dosing considerations
- Give first dose and subsequent increases at bedtime to avoid syncope
- May take with food
Hypertension
Initial: 1 mg PO qHS
Maintenance: 1-5 mg/day or q12hr; may increase to ≤20 mg/day
Dosing considerations
- Give first dose and subsequent increases at bedtime to avoid syncope
- May take with food
Dosing Modifications
Hepatic impairment: Use with caution
Dosage Forms & Strengths
capsule
- 1mg
- 2mg
- 5mg
- 10mg
Hypertension (Off-label)
1 mg/day PO; increase dose gradually as necessary; up to maximum of 20 mg/day
Hypertension
Initial: 0.5 mg PO qHS and titrate to response
Dosing considerations
Avoid use for hypertension; high risk of orthostatic hypotension (Beers criteria)
May cause significant orthostatic hypotension and syncope
Lower initial doses than those used for nongeriatric adults, as well as gradual adjustments, are recommended for hypertension
Give first dose and subsequent increases at bedtime to avoid syncope
Adverse effects such as dry mouth and urinary complications can be bothersome in the elderly
May take with food
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Contraindicated (0)
Serious - Use Alternative (5)
- lofexidine
lofexidine, terazosin. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension.
- sildenafil
sildenafil increases effects of terazosin by pharmacodynamic synergism. Avoid or Use Alternate Drug. Risk of hypotension; separate sildenafil >25mg from alpha blocker by 4hr.
- tamsulosin
terazosin, tamsulosin. Either increases effects of the other by additive vasodilation. Avoid or Use Alternate Drug. Risk of hypotension.
- vardenafil
vardenafil increases effects of terazosin by pharmacodynamic synergism. Contraindicated. Risk of hypotension.
- yohimbe
yohimbe increases effects of terazosin by pharmacodynamic synergism. Contraindicated.
Monitor Closely (92)
- acebutolol
terazosin and acebutolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Additive hypotensive effects may occur when terazosin is used in combination with acebutolol.
- aceclofenac
aceclofenac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- acemetacin
acemetacin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- aldesleukin
aldesleukin increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Risk of hypotension.
- alfuzosin
alfuzosin and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- amifostine
amifostine, terazosin. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine.
- amlodipine
terazosin and amlodipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- asenapine
asenapine and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- aspirin
aspirin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- aspirin rectal
aspirin rectal decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- aspirin/citric acid/sodium bicarbonate
aspirin/citric acid/sodium bicarbonate decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- atenolol
terazosin and atenolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- avanafil
avanafil increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Risk of hypotension.
- benazepril
benazepril, terazosin. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- betaxolol
terazosin and betaxolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- bisoprolol
terazosin and bisoprolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- bretylium
terazosin, bretylium. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Each drug may cause hypotension.
- captopril
captopril, terazosin. Either increases effects of the other by Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response. Both drugs lower blood pressure. Monitor blood pressure.
- carbidopa
carbidopa increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Therapy with carbidopa, given with or without levodopa or carbidopa-levodopa combination products, is started, dosage adjustment of the antihypertensive drug may be required.
- carvedilol
terazosin and carvedilol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- celecoxib
celecoxib decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- celiprolol
terazosin and celiprolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- choline magnesium trisalicylate
choline magnesium trisalicylate decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- clevidipine
terazosin and clevidipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- diclofenac
diclofenac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- diflunisal
diflunisal decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- diltiazem
terazosin and diltiazem both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- doxazosin
doxazosin and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- enalapril
enalapril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- esmolol
terazosin and esmolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Additive hypotensive effects may occur when terazosin is used in combination with esmolol.
- etodolac
etodolac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- felodipine
terazosin and felodipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- fenoprofen
fenoprofen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- flurbiprofen
flurbiprofen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- fosinopril
fosinopril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- ibuprofen
ibuprofen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- ibuprofen IV
ibuprofen IV decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- iloperidone
iloperidone increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor.
- imidapril
imidapril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- indomethacin
indomethacin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- isradipine
terazosin and isradipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- ketoprofen
ketoprofen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- ketorolac
ketorolac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- ketorolac intranasal
ketorolac intranasal decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- labetalol
terazosin and labetalol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- levodopa
levodopa increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Consider decreasing dosage of antihypertensive agent.
- lisinopril
lisinopril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- lornoxicam
lornoxicam decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- lurasidone
lurasidone increases effects of terazosin by Other (see comment). Use Caution/Monitor. Comment: Potential for increased risk of hypotension with concurrent use. Monitor blood pressure and adjust dose of antihypertensive agent as needed.
- maraviroc
maraviroc, terazosin. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Increased risk of orthostatic hypotension.
- meclofenamate
meclofenamate decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- mefenamic acid
mefenamic acid decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- meloxicam
meloxicam decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- methylphenidate
methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Monitor BP.
- metoprolol
terazosin and metoprolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- moexipril
moexipril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- moxisylyte
moxisylyte and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- nabumetone
nabumetone decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- nadolol
terazosin and nadolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- naproxen
naproxen decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- nebivolol
terazosin and nebivolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- nicardipine
terazosin and nicardipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- nifedipine
terazosin and nifedipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- nisoldipine
terazosin and nisoldipine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- nitroglycerin rectal
nitroglycerin rectal, terazosin. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Observe for possible additive hypotensive effects during concomitant use. .
- oxaprozin
oxaprozin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- oxymetazoline topical
oxymetazoline topical increases and terazosin decreases sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Effect of interaction is not clear, use caution. Use Caution/Monitor.
- parecoxib
parecoxib decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- penbutolol
terazosin and penbutolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- perindopril
perindopril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- phenoxybenzamine
phenoxybenzamine and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- phentolamine
phentolamine and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- pindolol
terazosin and pindolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- piroxicam
piroxicam decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- prazosin
prazosin and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- propranolol
terazosin and propranolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Additive hypotensive effects may occur when terazosin is used in combination with propranolol.
- pseudoephedrine
pseudoephedrine decreases effects of terazosin by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor.
- quinapril
quinapril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- ramipril
ramipril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- salicylates (non-asa)
salicylates (non-asa) decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- salsalate
salsalate decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- silodosin
silodosin and terazosin both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- sotalol
terazosin and sotalol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Additive hypotensive effects may occur when terazosin is used in combination with sotalol.
- sulfasalazine
sulfasalazine decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- sulindac
sulindac decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- tadalafil
tadalafil increases effects of terazosin by pharmacodynamic synergism. Use Caution/Monitor. Risk of hypotension.
- timolol
terazosin and timolol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely.
- tolfenamic acid
tolfenamic acid decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- tolmetin
tolmetin decreases effects of terazosin by pharmacodynamic antagonism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis.
- trandolapril
trandolapril, terazosin. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Exaggerated first dose hypotensive response.
- verapamil
terazosin and verapamil both increase anti-hypertensive channel blocking. Use Caution/Monitor.
- zotepine
terazosin and zotepine both increase anti-hypertensive channel blocking. Use Caution/Monitor.
Minor (7)
- brimonidine
brimonidine increases effects of terazosin by pharmacodynamic synergism. Minor/Significance Unknown.
- butcher's broom
terazosin, butcher's broom. Either decreases effects of the other by Mechanism: pharmacodynamic antagonism. Minor/Significance Unknown.
- ethanol
terazosin, ethanol. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypotension, esp. in Asian pts.
- phenylephrine
terazosin, phenylephrine. Either decreases effects of the other by Mechanism: pharmacodynamic antagonism. Minor/Significance Unknown.
- phenylephrine PO
terazosin, phenylephrine PO. Either decreases effects of the other by Mechanism: pharmacodynamic antagonism. Minor/Significance Unknown.
- tizanidine
tizanidine increases effects of terazosin by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypotension.
- treprostinil
treprostinil increases effects of terazosin by pharmacodynamic synergism. Minor/Significance Unknown.
Adverse Effects
>10%
Dizziness (10-20%)
Asthenia (2-13%)
1-10%
Hypotension (3-7%)
Rhinitis/nasal congestion (2-6%)
Lightheadedness (3-5%)
Somnolence (3-5%)
Palpitation (4%)
Nausea (2-4%)
Edema (3%)
Sinusitis (3%)
Dyspnea (2-3%)
Fatigue (2.5%)
Headache (2.5%)
Back pain (2.4%)
Flulike syndrome (2.4%)
Tachycardia (2%)
Amblyopia (1-2%)
Blurred vision (1-2%)
Impotence (1-2%)
Syncope (1%)
Warnings
Contraindications
Hypersensitivity to terazosin, other quinazolines
Cautions
Carcinoma of the prostate and BPH cause many of the same symptoms; these two diseases frequently co-exist; patients thought to have BPH should be examined prior to starting therapy to rule out presence of carcinoma of the prostate
Therapy can cause marked lowering of blood pressure, especially postural hypotension, and syncope in association with first dose or first few days of therapy; a similar effect can be anticipated if therapy is interrupted for several days and then restarted; to decrease likelihood of syncope or excessive hypotension, treatment should always be initiated at a low dose (1 mg) and increased slowly; additional antihypertensive agents should be added with caution; patient should be cautioned to avoid situations, such as driving or hazardous tasks, where injury could result should syncope occur during initiation of therapy
If syncope occurs, the patient should be placed in a recumbent position and treated supportively as necessary; there is evidence that orthostatic effect is greater, even in chronic use, shortly after dosing; the risk of the events is greatest during initial seven days of treatment, but continues at all time intervals
While syncope is the most severe orthostatic effect, other symptoms of lowered blood pressure, such as dizziness, lightheadedness and palpitations, are more common; patients with occupations in which such events represent potential problems should be treated with particular caution
May cause CNS depression, which may impair physical or mental abilities; use caution when performing tasks that may require mental alertness, including driving or operating heavy machinery
May exacerbate heart failure
Concomitant administration with PDE-5 inhibitor (eg, sildenafil) can result in additive blood pressure-lowering effects and symptomatic hypotension; initiate PDE-5 inhibitor therapy at lowest dose
Risk of priapism (rare); because this condition can lead to permanent impotence if not promptly treated, patients must be advised about seriousness of the condition
Pregnancy & Lactation
Pregnancy category: C
Lactation: Not known if excreted into breast milk; use caution
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Blocks postsynaptic alpha-1 receptor; alpha blockade causes arterial and venous dilation
Selective agents cause less tachycardia than do nonselective agents
Absorption
Bioavailability: 90%
Onset (hypertension): 3 hr
Onset (benign prostate hyperplasia): 2 weeks
Duration: 24 hr
Peak response (benign prostate hyperplasia): 4-6 weeks
Peak plasma time: 1 hr
Distribution
Protein bound: 90-94%
Vd: 25-30 L
Metabolism
Metabolized extensively via hydrolysis, O-demethylation, and N-dealkylation in liver
Metabolites: 6- and 7-O-demethyl terazosin, piperazine derivative, diamine metabolite
Elimination
Half-life: 9-12 hr
Renal clearance: 9-12.5 mL/min
Excretion: Feces (55-60%); urine (40%)
Images
| BRAND | FORM. | UNIT PRICE | PILL IMAGE |
|---|---|---|---|
| terazosin oral - | 5 mg capsule |  | |
| terazosin oral - | 2 mg capsule |  | |
| terazosin oral - | 10 mg capsule |  | |
| terazosin oral - | 1 mg capsule |  | |
| terazosin oral - | 5 mg capsule |  | |
| terazosin oral - | 5 mg capsule |  | |
| terazosin oral - | 2 mg capsule |  | |
| terazosin oral - | 1 mg capsule |  | |
| terazosin oral - | 5 mg capsule |  | |
| terazosin oral - | 1 mg capsule |  | |
| terazosin oral - | 10 mg capsule |  | |
| terazosin oral - | 10 mg capsule |  | |
| terazosin oral - | 10 mg capsule |  | |
| terazosin oral - | 2 mg capsule |  | |
| terazosin oral - | 1 mg capsule |  | |
| terazosin oral - | 2 mg capsule |  | |
| terazosin oral - | 10 mg capsule |  |
Copyright © 2010 First DataBank, Inc.
Patient Handout
terazosin oral
TERAZOSIN - ORAL
(ter-AY-zoe-sin)
COMMON BRAND NAME(S): Hytrin
USES: Terazosin is used alone or with other drugs to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication works by relaxing blood vessels so blood can flow more easily.Terazosin is also used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It does not shrink the prostate, but it works by relaxing the muscles in the prostate and part of the bladder. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate often or urgently (including during the middle of the night).Terazosin belongs to a class of drugs known as alpha blockers.
HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking terazosin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.Take this medication by mouth with or without food as directed by your doctor, usually once daily at bedtime.If you are taking this drug for the first time, do not take more than 1 milligram to start. Terazosin may cause a sudden drop in your blood pressure, which could lead to dizziness or fainting. This risk is higher when taking your first dose. To avoid injury related to dizziness or fainting, take your first dose of terazosin at bedtime.Your doctor will start this medication at a low dose and gradually increase your dose. Any time your dose is increased or if you restart treatment after you have stopped it, take your first dose at bedtime unless otherwise directed to lessen the risk of injury related to dizziness or fainting. Also during these times, avoid situations where you may be injured if you faint.The dosage is based on your medical condition and response to treatment.Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. If you miss taking terazosin for a few days, you may need to restart treatment at the low dose and gradually increase your dose again. Consult your doctor for more details.If you are taking this medication for high blood pressure, keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick. Tell your doctor if your blood pressure readings remain high or increase.If you are taking this drug for an enlarged prostate, it may take 2 to 4 weeks to see an improvement in your symptoms, and up to 6 weeks before you see the full benefit of this drug. Tell your doctor if your condition does not improve or if it worsens.
SIDE EFFECTS: Dizziness, lightheadedness, tiredness, nausea, drowsiness, blurred vision, headache, or stuffy nose may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular heartbeat, burning/tingling in the hands/feet, sexual function problems, swelling of the ankles/hands/feet, unexpected weight gain.Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before taking terazosin, tell your doctor or pharmacist if you are allergic to it; or to other alpha blockers such as doxazosin or prazosin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure/fainting, certain eye problems (cataracts, glaucoma).This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. You should avoid driving or hazardous tasks for 12 hours after the first dose, after your dose is increased, and when this medication is restarted after it has been stopped. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).Before having surgery (including cataract/glaucoma eye surgery), tell your doctor or dentist if you are taking or have ever taken this medication, and about all the other products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially dizziness, fainting, and low blood pressure when getting up from a sitting or lying position. These side effects can increase the risk of falling.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: other alpha blocker drugs (such as prazosin, tamsulosin).If you are also taking a drug to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may need to adjust your medications to minimize this risk.Some products have ingredients that could raise your blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).
OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting.
NOTES: Do not share this medication with others.If you have high blood pressure, lifestyle changes that may help this medication work better include exercising, stopping smoking, and eating a low-cholesterol/low-fat diet. Consult your doctor for more details.Have your blood pressure checked regularly while taking this medication. Learn how to monitor your own blood pressure at home, and share the results with your doctor.Lab and/or medical tests (such as prostate exams, blood pressure) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.
MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up. See also How to Use section.
STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Capsules should be stored between 68-77 degrees F (20-25 degrees C), because they may soften or melt if stored at higher than recommended temperatures. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised May 2023. Copyright(c) 2023 First Databank, Inc.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Formulary
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