Suggested Dosing
Follow Mfr's instructions
General Dosing Guidelines
300-500 mg PO BID/TID
Osteoarthritis
Extract: 333 mg TID PO
Rheumatoid Arthritis
Extract: 3600 mg/day
Ulcerative Colitis
Gum Resin preparation: 350 mg TID PO
Bronchial Asthma
300 mg TID PO
Generally 300-500 mg PO BID/TID, higher in IBD
Suggested Uses
Osteoarthritis, rheumatoid arthritis, asthma, inflammatory bowel disease, diuretic, painful menstration
Efficacy
Clinical trials have shown beneficial evidence for all of the above uses but of varying consistency & reliability
Adverse Effects
Frequency Not Defined
Diarrhea
Nausea etc
Warnings
Contraindications
Pregnancy
Cautions
May be emmenagogue & abortificient
Pregnancy & Lactation
Pregnancy Category: avoid
Lactation: N/A
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Boswellic acid, the major constituent is thought to contain pharmacologic potency
Inhibits 5-lipoxygenase in vitro & in animal studies
Antiinflammatory
