Suggested Dosing
No Typical Dosage
Capsule: 1-6 g whole herb PO qDay
Tea form: 3 cups qD (1-6g whole herb)
Tincture: 2-4 mL PO TID
Suggested Uses
Adaptogen: adapt to internal/external stressors, fight fatigue, increase stamina
Efficacy
Insufficient information
Interactions
Interaction Checker
No Results

Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor

Contraindicated (0)
Serious - Use Alternative (0)
Monitor Closely (0)
Minor (26)
- amobarbital
ashwagandha increases effects of amobarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- azelastine
ashwagandha increases effects of azelastine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- brompheniramine
ashwagandha increases effects of brompheniramine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- butabarbital
ashwagandha increases effects of butabarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- butalbital
ashwagandha increases effects of butalbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- carbinoxamine
ashwagandha increases effects of carbinoxamine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- chloral hydrate
ashwagandha increases effects of chloral hydrate by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- chlorpheniramine
ashwagandha increases effects of chlorpheniramine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- cinnarizine
ashwagandha increases effects of cinnarizine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- clemastine
ashwagandha increases effects of clemastine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- cyclizine
ashwagandha increases effects of cyclizine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- cyproheptadine
ashwagandha increases effects of cyproheptadine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- dexchlorpheniramine
ashwagandha increases effects of dexchlorpheniramine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- dexmedetomidine
ashwagandha increases effects of dexmedetomidine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- dextroamphetamine
ashwagandha increases effects of dextroamphetamine by unspecified interaction mechanism. Minor/Significance Unknown.
- dimenhydrinate
ashwagandha increases effects of dimenhydrinate by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- diphenhydramine
ashwagandha increases effects of diphenhydramine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- doxylamine
ashwagandha increases effects of doxylamine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- hydroxyzine
ashwagandha increases effects of hydroxyzine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- pentobarbital
ashwagandha increases effects of pentobarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- phenobarbital
ashwagandha increases effects of phenobarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- primidone
ashwagandha increases effects of primidone by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- promethazine
ashwagandha increases effects of promethazine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- secobarbital
ashwagandha increases effects of secobarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- triclofos
ashwagandha increases effects of triclofos by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
- triprolidine
ashwagandha increases effects of triprolidine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.
Warnings
Contraindications
Hypertension
Pregnancy
Pregnancy & Lactation
Pregnancy Category: X
Lactation: N/A
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Withanolides, ipuranol, withaniol anti-inflammatory, decrease BP, resp. stimulation, smooth muscle relaxation