Ashwagandha (Herb/Suppl)

Brand and Other Names:Indian Ginseng, Withania, more...Withania Somnifera

Suggested Dosing

No Typical Dosage

Capsule: 1-6 g whole herb PO qDay

Tea form: 3 cups qD (1-6g whole herb)

Tincture: 2-4 mL PO TID

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Suggested Uses

Adaptogen: adapt to internal/external stressors, fight fatigue, increase stamina

Efficacy

Insufficient information

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Interactions

Interaction Checker

and Ashwagandha

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (0)

                  Minor (26)

                  • amobarbital

                    ashwagandha increases effects of amobarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • azelastine

                    ashwagandha increases effects of azelastine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • brompheniramine

                    ashwagandha increases effects of brompheniramine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • butabarbital

                    ashwagandha increases effects of butabarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • butalbital

                    ashwagandha increases effects of butalbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • carbinoxamine

                    ashwagandha increases effects of carbinoxamine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • chloral hydrate

                    ashwagandha increases effects of chloral hydrate by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • chlorpheniramine

                    ashwagandha increases effects of chlorpheniramine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • cinnarizine

                    ashwagandha increases effects of cinnarizine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • clemastine

                    ashwagandha increases effects of clemastine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • cyclizine

                    ashwagandha increases effects of cyclizine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • cyproheptadine

                    ashwagandha increases effects of cyproheptadine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • dexchlorpheniramine

                    ashwagandha increases effects of dexchlorpheniramine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • dexmedetomidine

                    ashwagandha increases effects of dexmedetomidine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • dextroamphetamine

                    ashwagandha increases effects of dextroamphetamine by unspecified interaction mechanism. Minor/Significance Unknown.

                  • dimenhydrinate

                    ashwagandha increases effects of dimenhydrinate by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • diphenhydramine

                    ashwagandha increases effects of diphenhydramine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • doxylamine

                    ashwagandha increases effects of doxylamine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • hydroxyzine

                    ashwagandha increases effects of hydroxyzine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • pentobarbital

                    ashwagandha increases effects of pentobarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • phenobarbital

                    ashwagandha increases effects of phenobarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • primidone

                    ashwagandha increases effects of primidone by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • promethazine

                    ashwagandha increases effects of promethazine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • secobarbital

                    ashwagandha increases effects of secobarbital by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • triclofos

                    ashwagandha increases effects of triclofos by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

                  • triprolidine

                    ashwagandha increases effects of triprolidine by pharmacodynamic synergism. Minor/Significance Unknown. May enhance CNS depression.

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                  Warnings

                  Contraindications

                  Hypertension

                  Pregnancy

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                  Pregnancy & Lactation

                  Pregnancy Category: X

                  Lactation: N/A

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Mechanism of Action

                  Withanolides, ipuranol, withaniol anti-inflammatory, decrease BP, resp. stimulation, smooth muscle relaxation

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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.