cadexomer iodine (OTC)

Brand and Other Names:Iodosorb
  • Print

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

gel

  • 0.9% iodine

ointment

  • 4.7%

Cleaning Wet Ulcers and wounds

Spread in1/8-1/4 inch to dry sterile gauze; apply gauze on wound

No more than 50 g per application; no more than 150 g/week

Change 3 times/week or when color turns to yellow/gray

Antiseptic for Minor Cuts, Scrapes, Burns

Apply small amount to affected area qDay to q8hr

Safety & efficacy not established

Next:

Interactions

Interaction Checker

and cadexomer iodine

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (0)

                  Minor (12)

                  • amiloride

                    cadexomer iodine, amiloride. Mechanism: decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.

                  • drospirenone

                    cadexomer iodine, drospirenone. Mechanism: decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.

                  • iodine (radioactive)

                    cadexomer iodine, iodine (radioactive). Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Additive hypothyroid effects.

                  • iodoquinol

                    iodoquinol increases effects of cadexomer iodine by pharmacodynamic synergism. Minor/Significance Unknown.

                  • lithium

                    cadexomer iodine, lithium. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Additive hypothyroid effects.

                  • methimazole

                    cadexomer iodine, methimazole. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Additive hypothyroid effects.

                  • potassium acid phosphate

                    cadexomer iodine increases levels of potassium acid phosphate by decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.

                  • potassium chloride

                    cadexomer iodine increases levels of potassium chloride by decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.

                  • potassium citrate

                    cadexomer iodine increases levels of potassium citrate by decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.

                  • propylthiouracil

                    cadexomer iodine, propylthiouracil. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Additive hypothyroid effects.

                  • spironolactone

                    cadexomer iodine, spironolactone. Mechanism: decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.

                  • triamterene

                    cadexomer iodine, triamterene. Mechanism: decreasing renal clearance. Minor/Significance Unknown. Hyperkalemia.

                  Previous
                  Next:

                  Adverse Effects

                  Frequency Not Defined

                  Transient slight/moderate pain

                  Redness or swelling at application site

                  Previous
                  Next:

                  Warnings

                  Contraindications

                  Iodine sensitivity

                  Hashimoto's thyroiditis, history of Graves disease or nontoxic goiter

                  Pregnancy, lactation

                  Dry wounds

                  Breast feeding

                  Cautions

                  Limit use of a tube to one patient

                  NMT 3 mth

                  Previous
                  Next:

                  Pregnancy & Lactation

                  Pregnancy Category: do not use

                  Lactation: do not nurse

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

                  Previous
                  Next:

                  Pharmacology

                  Mechanism of Action

                  Releases iodine that has broad spectrum germicidal function

                  Hydrophilic cadexomer beads allows for slow release of iodine into the wound and absorption of fluid, bacteria, and other substances from the wound

                  Pharmacokinetics

                  Distribution: Thyroid (primarily)

                  Previous
                  Next:

                  Images

                  Pricing & Images are not currently available for this monograph.
                  Previous
                  Next:

                  Patient Handout

                  Patient Education
                  cadexomer iodine topical

                  NO MONOGRAPH AVAILABLE AT THIS TIME

                  USES: Consult your pharmacist.

                  HOW TO USE: Consult your pharmacist.

                  SIDE EFFECTS: Consult your pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

                  PRECAUTIONS: Consult your pharmacist.

                  DRUG INTERACTIONS: Consult your pharmacist.Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

                  OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

                  NOTES: No monograph available at this time.

                  MISSED DOSE: Consult your pharmacist.

                  STORAGE: Consult your pharmacist.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

                  Information last revised July 2016. Copyright(c) 2022 First Databank, Inc.

                  IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

                  Previous
                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.