homatropine (Discontinued)

Brand and Other Names:Homatropine (Isopto Homatropine), homatropine ophthalmic, more...IsoptoHomatropine
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ophthalmic solution

  • 2%
  • 5%

Cycloplegia/Mydriasis for Refraction

Discontinued by manufacturer (12/18/2012)

1-2 gtt 2% solution, or 1 gtt 5% solution, may repeat at 10-15 min intervals if necessary; not to exceed 5 doses

Uveitis

1-2 gtt of 2 or 5% solution in eye 2-3 times daily up to q4hr for severe uveitis

Dosage Forms & Strengths

ophthalmic solution

  • 2%
  • 5%

Cycloplegia/Mydriasis

1-2 gtt 2% solution, may repeat 10-15 min intervals if necessary; not to exceed 5 doses

Uveitis

1 gtt 2% solution 2-3 times daily

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Interactions

Interaction Checker

and homatropine

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Increased IOP

            Follicular conjunctivitis

            Vascular congestion

            Edema

            Xerostomia

            Burning

            Irritation

            Stinging

            Blurred vision

            Thirst

            Exudate

            Eczematoid dermatitis

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            Warnings

            Contraindications

            Sensitivity to homatropine or components, primary glaucoma or narrow angle glaucoma

            Cautions

            Discontinue the drug if signs or symptoms of sensitivity occur during treatment or if irritation persists or increases

            Use with extreme caution in infants and young children because of increased susceptibility to systemic effects

            Excessive use may cause CNS adverse effects including delirium, confusion, coma, or agitation

            Use appropriate eye protection (may cause sensitivity to light)

            Use caution in Down syndrome patients (susceptible to angle closure glaucoma)

            Use caution in patients with keratoconus; may result in fixed pupil dilation

            Elderly are susceptible to side effects; use caution

            Use caution in infants and young children due to susceptibility of systemic side effects

            Discontinue if experiences pain within the eye

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: Excretion in milk unknown; not recommended

            Pregnancy Categories

            A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA: Information not available.

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            Pharmacology

            Mechanism of Action

            Blocks the responses of the sphincter muscle of iris & ciliary muscle of the lens to cholinergic stimulation, thereby producing mydriasis and cycloplegia

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            Images

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            Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.