pramoxine topical (OTC)

Brand and Other Names:Itch-X Gel, Itch-X Spray, more...PrameGel, Prax, Sarna Sensitive Anti-Itch, proctoFoam, Azo Itch Relief Maximum Strength Analgesic Cream, Eczemin
  • Print

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

topical cream

  • 1%

topical gel

  • 1%

topical lotion

  • 1%

topical spray

  • 1%

Topical Pain

Apply to affected area up to 3-4 times/day

Feminine Itching

Apply small amount to external vaginal area up to 4 times/day

Dosage Forms & Strengths

topical cream

  • 1%

topical gel

  • 1%

topical lotion

  • 1%

topical spray

  • 1%

Topical Pain

<2 years: Safety and efficacy not established

>2 years: Apply to affected area up to 3-4 times/day

Next:

Adverse Effects

Frequency Not Defined

Irritation

Pruritus

Contact dermatitis

Previous
Next:

Warnings

Contraindications

Hypersensitivity

Cautions

Do not exceed daily recommended dosage

Do not use in eyes or nose

Do not apply to large areas of body

Previous
Next:

Pregnancy & Lactation

Pregnancy category: C

Lactation: Unknown if excreted in breast milk; exercise caution

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Previous
Next:

Pharmacology

Mechanism of Action

Local anesthetic; stabilizes neuronal membranes and prevent generation/conduction of nerve impulses by reducing sodium permeability and increasing action potential threshold

Absorption

Onset: 32-5 min

Previous
Next:

Images

Previous
Next:
Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.