sulfacetamide topical (Rx)

Brand and Other Names:Klaron, Ovace Plus, more...Ovace Plus Shampoo, Ovace Plus Wash, Ovace Wash
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

lotion

  • 10% (Klaron)

cream

  • 10% (Ovace Plus)

shampoo

  • 10% (Ovace Plus Shampoo)

wash, oil in water emulsion

  • 10% (Ovace Plus Wash)

wash

  • 10% (Ovace Wash)

Acne Vulgaris

Klaron: Apply thin film topically to affected areas BID

Seborrheic Dermatitis

Indicated for scaling dermatoses (eg, seborrheic dermatitis, seborrhea sicca [dandruff]); also indicated for the treatment of secondary bacterial infections of the skin due to organisms susceptible to sulfonamides

Ovace Plus Cream: Apply to affeted areas BID x8-10 days

Ovace Wash, Ovace Plus Wash: Wash affected areas BID x 8-10 days

For cream or wash, as condition subsides, lengthen interval between applications to once or twice weekly or every other week to prevent recurrence

Ovace Plus Shampoo: Apply to wet hair and massage vigorously into scalp; rinse thoroughly; use at least twice/week

Administration

Avoid contact with eyes or mucous membranes

Dosage Forms & Strengths

lotion

  • 10% (Klaron)

cream

  • 10% (Ovace Plus)

shampoo

  • 10% (Ovace Plus Shampoo)

wash, oil in water emulsion

  • 10% (Ovace Plus Wash)

wash

  • 10% (Ovace Wash)

Acne Vulgaris

<12 years: Safety and efficacy not established

Klaron ≥12 years: Apply thin film topically to affected areas BID

Seborrheic Dermatitis

Indicated for scaling dermatoses (eg, seborrheic dermatitis, seborrhea sicca [dandruff]); also indicated for the treatment of secondary bacterial infections of the skin due to organisms susceptible to sulfonamides

<12 years: Safety and efficacy not established

≥12 years

  • Ovace Plus Cream: Apply to affeted areas BID x8-10 days
  • Ovace Wash, Ovace Plus Wash: Wash affected areas BID x 8-10 days
  • For cream or wash, as condition subsides, lengthen interval between applications to once or twice weekly or every other week to prevent recurrence
  • Ovace Plus Shampoo: Apply to wet hair and massage vigorously into scalp; rinse thoroughly; use at least twice/week

Administration

Avoid contact with eyes or mucous membranes

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Interactions

Interaction Checker

and sulfacetamide topical

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            1-10%

            Erythema

            Itching

            Edema

            Local irritation

            Stinging

            Burning

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            Warnings

            Contraindications

            Hypersensitivity

            Cautions

            Avoid contact with eyes or mucous membranes

            Severe reactions to sulfonamides including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias reported

            Avoid UV exposure

            Contains sodium metabisulfite that is known to cause allergic reactions

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: not known whether excreted in breast milk, use caution

            Pregnancy Categories

            A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA: Information not available.

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            Pharmacology

            Mechanism of Action

            Para-aminobenzoic acid (PABA) inhibitor; restricts folic acid synthesis required for bacterial growth

            Absorption

            4%

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            Images

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            Formulary

            FormularyPatient Discounts

            Adding plans allows you to compare formulary status to other drugs in the same class.

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            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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            Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.