psyllium (OTC)

Brand and Other Names:Metamucil, Konsyl, more...Reguloid
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

Amount expressed as soluble fiber

capsule

  • 400 mg (Reguloid)

packet, powder for dissolution

  • Konsyl: 60.3% (1 each)
  • Metamucil MultiHealth Fiber Oral: 58.12% (1 each)

bottle, powder for dissolution

  • Konsyl
    • 30.9% (per gram)
    • 60.3% (per gram)
    • 71.67% (per gram)
  • Konsyl-D
    • 52.3% (per gram)
  • Reguloid
    • 28.3% (per gram)
    • 48.57% (per gram)
    • 58.6% (per gram)

Constipation

Indicated for fiber supplementation, occasional constipation, or to help promote and maintain regularity

Dosage varies between products; check individual produce labeling; generally, initiate with lower dose and gradually increase according to symptoms and tolerability

2.5-30 g/day PO in divided doses

Reduce Risk of Coronary Heart Disease

Soluble fiber ≥7 g PO (psyllium seed husk ≥10.2 g) per day

Dietary Fiber Supplement

Indicated for daily fiber supplement

Daily recommended intake of total fiber (J Acad Nutr Diet. 2015)

19-50 years

  • Males: 38 g/day
  • Females: 25 g/day

≥51 years

  • Males: 30 g/day
  • Females: 21 g/day

Pregnancy: 28 g/day

Lactation: 29 g/day

Dosage Forms & Strengths

Amount expressed as soluble fiber

capsule

  • 400 mg (Reguloid)

packet, powder for dissolution

  • Konsyl: 60.3% (1 each)
  • Metamucil MultiHealth Fiber Oral: 58.12% (1 each)

bottle, powder for dissolution

  • Konsyl
    • 30.9% (per gram)
    • 60.3% (per gram)
    • 71.67% (per gram)
  • Konsyl-D
    • 52.3% (per gram)
  • Reguloid
    • 28.3% (per gram)
    • 48.57% (per gram)
    • 58.6% (per gram)

Constipation

Indicated for fiber supplementation, occasional constipation, or to help promote and maintain regularity

Dosage varies between products; check individual produce labeling; generally, initiate with lower dose and gradually increase according to symptoms and tolerability

6-11 years: 1.25-15 g/day PO in divided doses

≥12 years: 2.5-30 g/day PO in divided doses

Reduce Risk of Coronary Heart Disease

≥12 years: Soluble fiber ≥7 g (psyllium seed husk ≥10.2 g) PO per day

Dietary Fiber Supplement

Indicated for daily fiber supplement

Daily recommended intake of total fiber (J Acad Nutr Diet. 2015)

1-3 years: 19 g/day

4-8 years: 25 g/day

9-13 years

  • Males: 31 g/day
  • Females: 26 g/day

14-18 years

  • Males: 38 g/day
  • Females: 26 g/day
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Interactions

Interaction Checker

and psyllium

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (1)

                • metoclopramide intranasal

                  psyllium will decrease the level or effect of metoclopramide intranasal by Other (see comment). Use Caution/Monitor. Coadministration of metoclopramide intranasal with drugs that impair GI motility may decrease systemic absorption of metoclopramide. Monitor for reduced therapeutic effect.

                Minor (1)

                • sodium picosulfate

                  psyllium decreases effects of sodium picosulfate by Mechanism: unspecified interaction mechanism. Minor/Significance Unknown.

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                Adverse Effects

                1-10%

                Abdominal cramping

                Constipation

                Flatulence

                Frequency Not Defined

                Impaction

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                Warnings

                Contraindications

                Hypersensitivity, GI obstruction, fecal impaction, symptoms of appendicitis or acute surgical abdomen, GI ulceration, dysphagia, rectal bleeding

                Cautions

                Powder should be mixed in 8oz of water or juice

                Pts with phenylketonuria as sugar free products contain phenylalanine

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                Pregnancy & Lactation

                Pregnancy Category: B

                Lactation: no data available; not absorbed, therefore it is unlikely to pose the risk in breast-feeding

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Mechanism of Action

                Bulk-producing laxative

                Absorption

                Onset: 12-72 hr

                Metabolism

                Not absorbed from GI tract

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                Administration

                Oral Administration

                Powder for dissolution: Drink at least 8 ounces of liquid with each dose; mix in a glass of water or juice

                Capsule: Swallow 1 capsule at a time; for ≥1 dose, divide throughout the day

                Separate dose by at least 2 hr from other drug therapies

                Storage

                All formulations: Store at room temperature; protect from moisture

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                Patient Handout

                A Patient Handout is not currently available for this monograph.
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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.