Lacrisert (hydroxypropyl cellulose ophthalmic) dosing, indications, interactions, adverse effects, and more.

Sections

Sections hydroxypropyl cellulose ophthalmic
Dosing & Uses
Adverse Effects
Warnings
Pregnancy
Pharmacology
Administration
Images
Patient Handout
Formulary

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ophthalmic insert

5mg/insert

Dry Eye Syndrome

Indicated for moderate-to-severe dry eye syndromes, including keratoconjunctivitis sicca

Using supplied applicator, place 1 ophthalmic insert in each eye qDay; some patients may require twice daily dosing

Optimal results may not be observed for several weeks

Safety and efficacy not established

Frequency Not Defined

Transient blurred vision

Ocular discomfort or irritation

Matting or stickiness of eyelashes

Photophobia

Hypersensitivity

Edema of the eyelids

Hyperemia

Contraindications

Hypersensitivity

Cautions

Carefully follow instructions for inserting and removing

Improper placement may cause corneal abrasion

Transient blurred vision common after insertion, caution when operating hazardous machinery or driving

May be inadvertently expelled from the eye, especially in patients with shallow conjunctival fornices

Avoid rubbing the eye(s) containing insert, especially upon awakening, so as not to dislodge or expel the insert; if required, another insert may be administered

Not for use in conjunction with hot laser treatment

If solution dries on optical surfaces, let them stand in cool water before cleansing

Pregnancy & Lactation

Pregnancy Category: A

Lactation: Unlikely to be distributed in breast milk

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Mechanism of Action

Ocular lubricant

Instructions

Using applicator supplied in package, place insert into inferior cul-de-sac of the eye beneath the base of the tarsus (not in apposition to the cornea, nor beneath the eyelid at the level of the tarsal plate)

If not properly positioned, it will be expelled into the interpalpebral fissure, and may cause symptoms of a foreign body

Images

No images available for this drug.

Patient Handout

A Patient Handout is not currently available for this monograph.

Formulary

FormularyPatient Discounts

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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

View explanations for tiers and restrictions

Tier	Description
1	This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2	This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC	NOT COVERED – Drugs that are not covered by the plan.

Code	Definition
PA	Prior Authorization Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL	Quantity Limits Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST	Step Therapy Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR	Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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