Suggested Dosing
Adjunctive Treatment for Cancer & HIV
1-4 mg IV/IM once/week
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Suggested Uses
Cancer, HIV
Efficacy
Possibly effective as adjunct when administered with didanosine in HIV
Insufficient Evidence to rate as adjunctive treatment for breast, gastric, prostate cancer. Preliminary evidence suggests improvement
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Interactions
Interaction Checker
and Lentinan
No Results
No Interactions Found
Interactions Found
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
All Interactions Sort By:
Contraindicated (0)
Serious - Use Alternative (0)
Monitor Closely (0)
Minor (0)
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Adverse Effects
Thrombocytopenia
Chronic large dose of whole shiitake can cause dermatitis, eosinophilia
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Warnings
Contraindications
Hypersensitivity
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Pregnancy & Lactation
Pregnancy Category: N/A
Lactation: N/A
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Previous
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Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Potentiates NK cell, macrophage, T-helper cell function
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
