Lentinan (Herb/Suppl)

Brand and Other Names:lentinus edodes

Suggested Dosing

Adjunctive Treatment for Cancer & HIV

1-4 mg IV/IM once/week

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Suggested Uses

Cancer, HIV

Efficacy

Possibly effective as adjunct when administered with didanosine in HIV

Insufficient Evidence to rate as adjunctive treatment for breast, gastric, prostate cancer. Preliminary evidence suggests improvement

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Interactions

Interaction Checker

and Lentinan

No Results

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    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Contraindicated (0)

              Serious - Use Alternative (0)

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                  Minor (0)

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                    Adverse Effects

                    Thrombocytopenia

                    Chronic large dose of whole shiitake can cause dermatitis, eosinophilia

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                    Warnings

                    Contraindications

                    Hypersensitivity

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                    Pregnancy & Lactation

                    Pregnancy Category: N/A

                    Lactation: N/A

                    Pregnancy Categories

                    A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                    B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                    C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                    D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                    X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                    NA: Information not available.

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                    Pharmacology

                    Metabolism: N/A

                    Excretion: N/A

                    Mechanism of Action

                    Potentiates NK cell, macrophage, T-helper cell function

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                    Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.