lifileucel (Pending FDA Approval)

Brand and Other Names:

Dosing & Uses

Melanoma

Pending FDA for advanced melanoma in patients who progressed on or after prior anti-PD-1/L1 therapy and targeted therapy

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Pharmacology

Mechanism of Action

Preparation of autologous tumor infiltrating lymphocytes (TILs) selected based on antigen specificity and tumor reactivity

Upon reintroduction of lifileucel into the patient, the TILs reinfiltrate the tumor, specifically recognize the tumor-associated antigens (TAAs), and initiate tumor cell lysis

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.