Dosing & Uses
Dosage Forms & Strengths
caplet
- 84mg
Magnesium Deficiency
168-336 mg PO divided BID
Renal Insufficiency
CrCl<30 mL/min: Use caution; monitor for hypermagnesemia
CrCl≥30 mL/min: Dose adjustement not necessary
Safety & efficacy not established
Interactions
Interaction Checker
No Results

Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor

Adverse Effects
Frequency Not Defined
Diarrhea
Warnings
Contraindications
Hypersensitivity
Cautions
Use with caution in patients with neuromuscular disease, including myasthenia gravis
Diets high in fat may cause decreased magnesium absorption
Monitor patients with severe renal impairment for magnesium toxicity; use caution
When used for self-medication, not for long term use; not for use if nausea, vomiting, or abdominal pain present; patients with impaired kidney function should use under the supervision of healthcare provider
Pregnancy & Lactation
Pregnancy
Not studied; magnesium crosses the placenta; effects of supplementation on neonate unknown
Lactation
Magnesium is present in breast milk; supplementation generally considered cmpatible with breastfeeding.
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Magnesium plays a role as a cofactor of various enzymatic activities, including metabolic reactions and protein synthesis. It also plays a role lipoprotein lipase activity, which is involved in cholesterol metabolism. .
Administration
Oral Administration
Administer with food