Dosing & Uses
Postoperative Pain
Pending FDA approval for postoperative pain in adults aged ≥18 years
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Pharmacology
Mechanism of Action
Acetaminophen: Nonopioid analgesic that activates the descending serotonergic inhibitory pathways in the CNS
Ibuprofen: Nonsteroidal anti-inflammatory with analgesic, antipyretic, and anti-inflammation properties; acts by reversibly inhibiting cyclooxygenase-1 and 2 (COX-1 and COX-2) enzymes resulting in decreased prostaglandin precursor formation
Fixed-dose combination is an effective alternative to opioid-based analgesics and is thought to be synergistic at managing acute and chronic pain
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Images
No images available for this drug.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
