Indication-specific dosing for mega taurine (taurine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Taurine
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

Congestive Heart Failure

2-6 g/day PO div BID-TID

Acute Hepatitis

4 g PO TID x 6 weeks

Treatment of Steatorrhea in Children with Cystic Fibrosis

30 mg/kg day x 4 months in addition to pancreatic enzyme supplementation

Cystathionine Beta-Synthase Deficient Homocystinuria (Orphan)

Indicated for treatment of cystathionine beta-synthase deficient homocystinuria

Orphan indication sponsor

Johan L. Van Hove, MD, PhD; Department of Pediatrics/University of Colorado DE; 13121 E. 17th Ave; PO Box 6508; Aurora, CO 80045

Suggested Uses

CHF, hypertension, hypercholesterolemia, cystic fibrosis, antiatherogenic effects

Other uses include seizure disorders (epilepsy), autism, ADHD, retinal degeneration, diabetes, alcoholism, improve mental performance & antioxidant.

Efficacy

In human clinical studies taurine lowered blood pressure

CHF: Seems to improve left ventricular function in patients with New York Heart Association functional class II to IV

Acute Hepatitis: Might improve liver function

In animal studies taurine lowered lipid levels, but human studies are contradictory

Interaction Checker

Enter a drug name and Taurine

No Results

No Interactions Found

Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

All Interactions Sort By:

Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (0)

Minor (35)

aldesleukin
aldesleukin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
bicalutamide
bicalutamide decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
capecitabine
capecitabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
cladribine
cladribine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
cytarabine
cytarabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
decitabine
decitabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
docetaxel
docetaxel decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
floxuridine
floxuridine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
fludarabine
fludarabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
fluorouracil
fluorouracil decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
flutamide
flutamide decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
fulvestrant
fulvestrant decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
gemcitabine
gemcitabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
goserelin
goserelin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
leuprolide
leuprolide decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
medroxyprogesterone
medroxyprogesterone decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
megestrol
megestrol decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
mercaptopurine
mercaptopurine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
nelarabine
nelarabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
nilutamide
nilutamide decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
oxaliplatin
oxaliplatin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
paclitaxel
paclitaxel decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
paclitaxel protein bound
paclitaxel protein bound decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
pegaspargase
pegaspargase decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown. Taurine was found to reduce platelet aggregation and may increase the risk of bleeding.
pentostatin
pentostatin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
pralatrexate
pralatrexate decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
tamoxifen
tamoxifen decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
thioguanine
thioguanine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
toremifene
toremifene decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
treosulfan
treosulfan decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
triptorelin
triptorelin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
vinblastine
vinblastine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
vincristine
vincristine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
vincristine liposomal
vincristine liposomal decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
vinorelbine
vinorelbine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.

aldesleukin
Minor (1)aldesleukin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
bicalutamide
Minor (1)bicalutamide decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
capecitabine
Minor (1)capecitabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
cladribine
Minor (1)cladribine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
cytarabine
Minor (1)cytarabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
decitabine
Minor (1)decitabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
docetaxel
Minor (1)docetaxel decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
floxuridine
Minor (1)floxuridine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
fludarabine
Minor (1)fludarabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
fluorouracil
Minor (1)fluorouracil decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
flutamide
Minor (1)flutamide decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
fulvestrant
Minor (1)fulvestrant decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
gemcitabine
Minor (1)gemcitabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
goserelin
Minor (1)goserelin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
leuprolide
Minor (1)leuprolide decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
medroxyprogesterone
Minor (1)medroxyprogesterone decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
megestrol
Minor (1)megestrol decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
mercaptopurine
Minor (1)mercaptopurine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
nelarabine
Minor (1)nelarabine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
nilutamide
Minor (1)nilutamide decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
oxaliplatin
Minor (1)oxaliplatin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
paclitaxel
Minor (1)paclitaxel decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
paclitaxel protein bound
Minor (1)paclitaxel protein bound decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
pegaspargase
Minor (1)pegaspargase decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown. Taurine was found to reduce platelet aggregation and may increase the risk of bleeding.
pentostatin
Minor (1)pentostatin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
pralatrexate
Minor (1)pralatrexate decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
tamoxifen
Minor (1)tamoxifen decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
thioguanine
Minor (1)thioguanine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
toremifene
Minor (1)toremifene decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
treosulfan
Minor (1)treosulfan decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
triptorelin
Minor (1)triptorelin decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
vinblastine
Minor (1)vinblastine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
vincristine
Minor (1)vincristine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
vincristine liposomal
Minor (1)vincristine liposomal decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.
vinorelbine
Minor (1)vinorelbine decreases levels of taurine by unspecified interaction mechanism. Minor/Significance Unknown.

Adverse Effects

None reported

Contraindications

Hypersensitivity

Cautions

Pregnancy, lactation

Monitor pts with CHF

Pregnancy & Lactation

Pregnancy Category: avoid use

Lactation: avoid use

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Metabolism: liver

Excretion: feces & urine

Mechanism of Action

Antioxidant, putative hypocholesterolemic, hypotensive, antiatherogenic & detoxifying activities

May also have steatorrhea-reducing activity in pts with cystic fibrosis & putative antidiabetic, inotropic & antiseizure activities

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

[CLOSE WINDOW]

Sections Taurine
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Taurine (Herb/Suppl)