butenafine (Rx, OTC)

Brand and Other Names:Lotrimin Ultra, Mentax, more...Mentax-TC
  • Print

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

cream

  • 1%

Tinea Pedis

Cream: Apply to affected areas BID for at least 1 week; not to exceed 4 weeks

Gel: Apply to affected area BID for 7 days

Solution: Apply to affected area BID for 7 days

Ringworm & Jock Itch (Tinea Corporis, Tinea Cruris)

Cream: Apply to affected area qDay/BID for at least 1 week; not to exceed 4 weeks

Gel: Apply to affected area once daily for 7 days

Solution: Apply to affected area qDay for 7 days in tinea corporis and tinea cruris; apply to affected areas BID for 7 days in tinea versicolor

Tinea (Pityriasis) Versicolor

Apply qDay for 2 weeks

Dosage Forms & Strengths

cream

  • 1%

Tinea Pedis

<12 years old: Safety & efficacy not established

>12 years old: As in adults

Ringworm & Jock Itch (Tinea Corporis, Tinea Cruris)

<12 years old: Safety & efficacy not established

>12 years old: As in adults

Next:

Adverse Effects

Common

burning

stinging

Less Common

contact dermatitis

erythema

irritation

itching

Previous
Next:

Warnings

Contraindications

Hypersensitivity

Previous
Next:

Pregnancy & Lactation

Pregnancy Category: C

Lactation: excretion in milk unknown; use with caution

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Previous
Next:

Pharmacology

Peak Plasma Time: 8-15 hr

Metabolism: liver

Excretion: urine

Mechanism of Action

Synthetic benzylamine topical antifungal similar to allylamines (terbinafine, naftifine) that inhibits intermediary in synthesis of ergosterol, an essential component of fungal cell membranes

Fungistatic

Previous
Next:

Images

BRAND FORM. UNIT PRICE PILL IMAGE
Lotrimin Ultra topical
-
1 % cream
Lotrimin Ultra topical
-
1 % cream
Mentax topical
-
1 % cream
Mentax topical
-
1 % cream

Copyright © 2010 First DataBank, Inc.

Previous
Next:

Patient Handout

Patient Education
butenafine topical

BUTENAFINE CREAM - TOPICAL

(bue-TEN-a-feen)

COMMON BRAND NAME(S): Lotrimin Ultra, Mentax

USES: This medication is used to treat a variety of fungal skin infections such as ringworm, athlete's foot, and jock itch. This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Butenafine is an antifungal that works by preventing the growth of fungus.Do not use this medication for the treatment of fungal nail infections.

HOW TO USE: Use this medication on the skin only. Clean and thoroughly dry the area to be treated. Apply a thin layer of the medication to and around the affected area and gently rub in, usually 1 to 2 times daily as directed on the product package. If you have any questions, ask your doctor or pharmacist. If your doctor has prescribed this medication to you, then use as directed. Wash your hands after using unless the area to be treated includes the hands. Do not wrap, cover, or bandage the area unless directed to do so by your doctor.Do not apply the medication in the eyes, nose, or mouth, inside the vagina, or on the scalp. If you do get the medication in those areas, flush with plenty of water.The dosage and length of treatment depends on the type of infection being treated.Do not apply more often or use longer than directed. This may increase the risk of side effects.Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time(s) each day.Continue to use this medication until the full treatment period is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.Inform your doctor if your condition worsens or does not improve after the treatment period.

SIDE EFFECTS: Burning, irritation, redness, or itching at the application site may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if any of these unlikely but serious side effects occur: blistering/swelling/oozing at the application site.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using this medication, tell your doctor or pharmacist if you are allergic to butenafine; or to allylamine antifungals (e.g., naftifine, terbinafine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: athlete's foot on the bottom/side of the foot.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

OVERDOSE: This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

NOTES: Do not share this medication with others.If your doctor has directed you to use this medication, use it for your current condition only. Do not use it later for another infection unless your doctor tells you to.If you are treating athlete's foot, make sure to wear well-fitting, ventilated shoes. Also, change shoes and socks at least once daily.When this medication is used to treat pityriasis, your normal skin color may not return right away. It may take several months after treatment is completed for your natural skin color to return.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

STORAGE: Store at room temperature away from light and heat. Consult your pharmacist or product labeling for exact temperature range. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised August 2021. Copyright(c) 2021 First Databank, Inc.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Previous
Next:

Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
Additional Offers
Email to Patient

From:

To:

The recipient will receive more details and instructions to access this offer.

By clicking send, you acknowledge that you have permission to email the recipient with this information.

Email Forms to Patient

From:

To:

The recipient will receive more details and instructions to access this offer.

By clicking send, you acknowledge that you have permission to email the recipient with this information.

Previous
Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.