metaproterenol (Rx)

Brand and Other Names:
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

tablet

  • 10mg
  • 20mg

syrup

  • 10mg/5mL
more...

Asthma, Reversible Bronchospasm

20 mg PO three/four times daily

Dosage Forms & Strengths

tablet

  • 10mg
  • 20mg

syrup

  • 10mg/5mL
more...

Asthma

PO

  • <2 years old: 0.4 mg/kg PO q8-12hr 
  • 2-6 years old: 1-3.5 mg/kg/day divided q6-8hr PO; not to exceed 10 mg/dose
  • 6-9 years old: 10 mg PO three/four times daily
  • >12 years old: 20 mg PO three times daily
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Interactions

Interaction Checker

and metaproterenol

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            >10%

            Tremor (2-17%)

            Tachycardia (6-17%)

            Nervousness (5-20%)

            1-10%

            Diaphoresis increased (4%)

            Headache (4%)

            Heartburn (4%)

            Palpation (4%)

            Pharyngitis (4%)

            Dizziness (1-4%)

            Insomnia (2%)

            Weakness (1%)

            Nausea (1-4%)

            Exacerbation of asthma (2%)

            <1%

            Chest pain

            Hypertension

            Weakness

            Syncope

            Spasms

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            Warnings

            Contraindications

            Hypersensitivity

            Tachycardia secondary to heart condition

            Cautions

            Reports of some patients who developed cramps in muscles of extremities which responded to potassium salts PO

            Use caution in recent MI, myocardial insufficiency, HTN, hyperthyroidism, severe cardiovascular disorder, seizure disorders

            Increases risk of hypokalemia;; use with caution

            Beta2-agonists may increase serum glucose; use caution

            Metered-dose inhalers that contain chlorofluorocarbons (CFCs) are currently being phased out in the United States; alternate inhalers without CFCs are available

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: Not known if excreted in breast milk, not recommended

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

            more...
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            Pharmacology

            Mechanism of Action

            Beta-2 receptor agonist with some beta-1 activity; stimulation of beta2 receptors may result in bronchial smooth muscle relaxation

            Pharmacokinetics

            Onset: 30 min (oral)

            Peak effect: 1 hr

            Duration: 2-6 hr

            Metabolism: Liver

            Metabolites: Metaproterenol-O-sulfate

            Excretion: Uurine (40%)

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            Images

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            Formulary

            FormularyPatient Discounts

            Adding plans allows you to compare formulary status to other drugs in the same class.

            To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

            Adding plans allows you to:

            • View the formulary and any restrictions for each plan.
            • Manage and view all your plans together – even plans in different states.
            • Compare formulary status to other drugs in the same class.
            • Access your plan list on any device – mobile or desktop.

            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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            Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.