Dosing & Uses
Dosage Forms & Strengths
triamcinolone/nystatin
topical cream/ointment
- (0.1%/100,000units)/g
Cutaneous Candidiasis
Apply cream/ointment BID; discontinue therapy when infection is under control or if symptoms persist for >25 days
Dosage Forms & Strengths
triamcinolone/nystatin
topical cream/ointment
- (0.1%/100,000units)/g
Cutaneous Candidiasis
As adults; apply cream/ointment BID; discontinue therapy when infection is under control or if symptoms persist for >25 days
Interactions
Interaction Checker
No Results

Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor

Adverse Effects
Frequency Not Defined
Blistering
Burning
Dryness
Acniform eruptions
Excessive discoloring of the skin
Excessive hair growth (especially on face)
Hair loss (especially on scalp)
Inflammation around the mouth
Inflammation of hair follicles
Irritation
Itching
Peeling
Prickly heat
Striae
Secondary infection
Skin inflammation
Softening of the skin
Stretch marks
Stretching or thinning of the skin
Warnings
Contraindications
Hypersensitivity
Cautions
For topical use only
Not for ophthalmic use
Avoid contact with eyes
Patient should report any signs of adverse reactions
Systemic absorption of topical corticosteroids has produced reversible hypothalmic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients
Conditions that augment systemic absorption include application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings
Patients receiving a large dose of any potent topical steroid applied to a large surface area should be evaluated periodically for evidence of HPA axis suppression by using urinary free cortisol and ACTH stimulation tests, and for impairment of thermal homeostasis; if HPA axis suppression or elevation of body temperature occurs, make attempt to withdraw drug, reduce frequency of application, or substitute for less potent steroid
Recovery of HPA axis function and thermal homeostasis are generally prompt and complete upon discontinuation of drug; infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids
Children may absorb proportionally larger amounts of topical corticosteroids and thus may be more susceptible to systemic toxicity
If irritation or hypersensitivity develops with combination of nystatin and triamcinolone acetonide, discontinue treatment and institute appropriate therapy
Pregnancy & Lactation
Pregnancy Category: unknown
Lactation: unknown if excreted in breast milk
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Triamcinolone potency
Medium
Very-high: clobetasol, diflorasone diacetate ointment 0.05%, halobetasol
High: betamethasone dipropionate 0.05%, amcinonide, fluocinonide, desoximetasone, mometasone, diflorasone emollient 0.05%, halcinonide
Medium: triamcinolone, betamethasone valerate 0.1%, fluticasone, flurandrenolide, fluocinolone 0.025%, hydrocortisone
Mild: hydrocortisone 0.5, 1, 2.5% base, desonide, alclometasone
Mechanism of Action
Nystatin: Antifungal activity
Triamcinolone: Corticosteroid; elicits antipruritic and anti-inflammatory effects
Images
Formulary
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