Dosing & Uses
Dosage Forms & Strengths
oral powder
- 100,000units/g
oral suspension
- 100,000units/mL
oral tablet
- 500,000units
capsule
- 500,000units
- 1,000,000units
Oropharyngeal Candidiasis
Oral suspension: 400,000-600,000 units PO q6hr; swish in mouth several minutes and then swallow
Intestinal Candidiasis
Oral tablets: 500,000-1,000,000 units q8hr
Powder: 1/8 to 1/4 teaspoonful in 1/2 cup of water (500,000-1,000,000 units) PO q8hr
Invasive Fungal Infections (Orphan)
Liposomal nystatin: Treatment of invasive fungal infections
Orphan indication sponsor
- The University of Texas, M.D. Anderson Cancer Center, Unit 038; Houston, TX 77030
Administration
Retain suspension in mouth as long as possible before swallowing
Dosage Forms & Strengths
oral powder
- 100,000units/g
oral suspension
- 100,000units/mL
oral tablet
- 500,000units
capsule
- 500,000units
- 1,000,000units
Oropharyngeal Candidiasis
Premature infants
- 100,000 units PO q6hr; paint suspension into recesses of the mouth
Infants
- 200,000 units PO q6hr (100,000 units in each side of mouth); paint suspension into recesses of the mouth
Children
- Oral suspension: 400,000-600,000 units PO q6hr; swish in mouth several minutes and then swallow
Intestinal Candidiasis
Oral tablets: 500,000 units-1,000,000 units q8hr
Powder: 1/8 to 1/4 teaspoonful in 1/2 cup of water (500,000-1,000,000 units) PO q8hr
Interactions
Interaction Checker
No Results

Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor

Contraindicated (1)
- allogeneic cultured keratinocytes/fibroblasts in bovine collagen
nystatin decreases effects of allogeneic cultured keratinocytes/fibroblasts in bovine collagen by Other (see comment). Contraindicated. Comment: Exposure to topical antibiotics has been shown to degrade Gintuit; if exposed, irrigate the wound thoroughly with saline and allow a suitable wash-out period to elapse before applying Gintuit.
Serious - Use Alternative (1)
- Saccharomyces boulardii
nystatin decreases effects of Saccharomyces boulardii by unspecified interaction mechanism. Avoid or Use Alternate Drug. Systemic or oral antifungals may decrease activity of probiotic.
Monitor Closely (1)
- voclosporin
voclosporin, nystatin. Either increases toxicity of the other by nephrotoxicity and/or ototoxicity. Modify Therapy/Monitor Closely. Coadministration with drugs associated with nephrotoxicity may increase the risk for acute and/or chronic nephrotoxicity.
Minor (0)
Adverse Effects
Frequency not defined
Diarrhea
Nausea
Stomach pain
Vomiting
Contact dermatitis
Stevens-Johnson syndrome
Hypersensitivity reactions
Warnings
Contraindications
Hypersensitivity
Cautions
Not for use in systemic mycoses
Discontinue therapy if irritation or sensitization observed during use
Pregnancy & Lactation
Pregnancy category: C
Lactation: Not known if excreted in breast milk; use caution
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Binds sterols in fungal cell membrane, altering permeability and thus causing cellular contents to leak
Absorption
Poor PO absorption
Onset: Symptom relief for oral candidiasis 24-72 hr
Elimination
Excretion: Feces (as unchanged drug)
Images
BRAND | FORM. | UNIT PRICE | PILL IMAGE |
---|---|---|---|
Nyamyc topical - | 100,000 unit/gram powder | ![]() | |
Nyamyc topical - | 100,000 unit/gram powder | ![]() | |
Nyamyc topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram cream | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram cream | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram cream | ![]() | |
nystatin topical - | 100,000 unit/gram cream | ![]() | |
nystatin topical - | 100,000 unit/gram cream | ![]() | |
nystatin topical - | 100,000 unit/gram cream | ![]() | |
nystatin topical - | 100,000 unit/gram cream | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram cream | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram powder | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram ointment | ![]() | |
nystatin topical - | 100,000 unit/gram cream | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
nystatin oral - | 500,000 unit tablet | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
nystatin oral - | 500,000 unit tablet | ![]() | |
nystatin oral - | 500,000 unit tablet | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
nystatin oral - | 100,000 unit/mL suspension | ![]() | |
Nystop topical - | 100,000 unit/gram powder | ![]() | |
Nystop topical - | 100,000 unit/gram powder | ![]() | |
Nystop topical - | 100,000 unit/gram powder | ![]() |
Copyright © 2010 First DataBank, Inc.
Patient Handout
nystatin oral
NYSTATIN TABLET - ORAL
(NYE-stat-in)
COMMON BRAND NAME(S): Mycostatin
USES: This medication is used to treat fungal infections in the stomach or intestines. Nystatin is an antifungal that works by stopping the growth of fungus.Nystatin tablets should not be used to treat fungal infections of the blood.
HOW TO USE: Take this medication by mouth with or without food as directed by your doctor, usually 3 times a day. It may take from several days to several months to complete treatment. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. The dosage is based on your medical condition and response to treatment.Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow the infection to continue, resulting in a return of the infection.Tell your doctor if your condition lasts after several days of treatment or gets worse at any time.
SIDE EFFECTS: Diarrhea, nausea, vomiting, or stomach upset may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including fast heartbeat, shortness of breath, muscle pain.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before taking nystatin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: HIV disease, diabetes, kidney disease.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
NOTES: Do not share this medication with others.This medication has been prescribed for your current condition only. Do not use it later for another infection unless your doctor tells you to.
MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
STORAGE: Store at room temperature away from heat and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised May 2023. Copyright(c) 2023 First Databank, Inc.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Formulary
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Adding plans allows you to:
- View the formulary and any restrictions for each plan.
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