simethicone (OTC)

Brand and Other Names:Mylicon, Phazyme, more...Gas X Extra Strength, Gas X Softgels, Gas X Thin Strips, Children's Gas X Tongue Twisters Thin Strips, Gas X, PediaCare Infant's Gas Relief Drops, St. Joseph Infant's Gas Relief
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

tablet

  • 80mg
  • 125mg

capsule

  • 125mg
  • 180mg

tablet, chewable

  • 80mg
  • 125mg

liquid, oral

  • 20mg/0.3mL

oral suspension

  • 20mg/0.3mL
  • 40mg/0.6mL

strip, orally disintegrating

  • 40mg
  • 62.5mg

Gas Retention in Gastrointestinal Tract

40-360 mg PO q6hr after meals and at bedtime PRN; not to exceed 500 mg/day

Dosage Forms & Strengths

tablet, chewable

  • 80mg
  • 125mg

capsule

  • 125mg
  • 180mg

tablet, chewable

  • 80mg
  • 125mg

liquid, oral

  • 20mg/0.3mL

oral suspension

  • 20mg/0.3mL
  • 40mg/0.6mL

strip, orally disintegrating

  • 40mg
  • 62.5mg

Gas Retention in Gastrointestinal Tract

<2 years: 20 mg (0.3 mL) PO q6hr after meals and at bedtime; not to exceed 240 mg/day

2-12 years: 40 mg (0.6 mL) PO q6hr after meals and at bedtime; not to exceed 480 mg/day

>12 years: 40-360 mg PO q6hr after meals and at bedtime; not to exceed 500 mg/day

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Adverse Effects

Frequency Not Defined

Loose stools

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Warnings

Contraindications

Hypersensitivity to simethicone

Cautions

Chewable tablet should be chewed thoroughly before swallowing; liquid-filled capsules should not be chewed

Can cause false-negative gastric guaiac test

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Pregnancy & Lactation

Pregnancy category: C

Lactation: Not absorbed systemically; not expected to be excreted in milk

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Changes surface tension of gas bubbles and causes collapse of foam bubbles, thus allowing easier passage of gas and preventing gas pockets in gastrointestinal tract

Elimination

Excretion: Feces (as unchanged drug); complete excretion within 24-48 hr

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Images

BRAND FORM. UNIT PRICE PILL IMAGE
Anti-Gas Ultra Strength oral
-
180 mg capsule
Anti-Gas Ultra Strength oral
-
180 mg capsule
Mi-Acid Gas Relief (simethicone) oral
-
80 mg chewable tablet
Mi-Acid Gas Relief (simethicone) oral
-
80 mg chewable tablet
Mi-Acid Gas Relief (simethicone) oral
-
80 mg chewable tablet
Phazyme oral
-
180 mg capsule
Gas-X oral
-
62.5 mg strip
Gas-X Extra Strength oral
-
125 mg chewable tablet
Gas-X Extra Strength oral
-
125 mg chewable tablet
Gas-X Extra Strength oral
-
125 mg capsule
simethicone oral
-
80 mg chewable tablet
simethicone oral
-
125 mg chewable tablet
simethicone oral
-
180 mg capsule
simethicone oral
-
80 mg chewable tablet
simethicone oral
-
125 mg capsule
simethicone oral
-
80 mg chewable tablet
Infants' Mylicon oral
-
40 mg/0.6 mL drops
Gas Relief 80 (simethicone) oral
-
80 mg chewable tablet
Gas Relief 80 (simethicone) oral
-
80 mg chewable tablet
Gas-X Ultra-Strength oral
-
180 mg capsule
Infants Gas Relief oral
-
40 mg/0.6 mL drops
Gas Relief Extra Strength oral
-
125 mg capsule
Gas Relief Extra Strength oral
-
125 mg chewable tablet
Gas Relief Extra Strength oral
-
125 mg chewable tablet
Gas Relief Extra Strength oral
-
125 mg capsule
Gas Relief Extra Strength oral
-
125 mg chewable tablet
Gas Relief Extra Strength oral
-
125 mg capsule
Gas Relief Extra Strength oral
-
125 mg capsule
Gas Relief Extra Strength oral
-
125 mg capsule
Gas Relief (simethicone) oral
-
80 mg chewable tablet
Gas Relief (simethicone) oral
-
40 mg/0.6 mL drops
Gas Relief (simethicone) oral
-
80 mg chewable tablet
Gas Relief (simethicone) oral
-
80 mg chewable tablet
Gas Relief (simethicone) oral
-
125 mg chewable tablet
Gas Relief (simethicone) oral
-
125 mg capsule
Gas Relief (simethicone) oral
-
125 mg capsule
Gas Relief (simethicone) oral
-
125 mg capsule
Gas Relief (simethicone) oral
-
80 mg chewable tablet
Gas Relief (simethicone) oral
-
180 mg capsule
Gas Relief (simethicone) oral
-
40 mg/0.6 mL drops

Copyright © 2010 First DataBank, Inc.

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Patient Handout

Patient Education
simethicone oral

SIMETHICONE DROPS - ORAL

(sye-METH-i-kone)

COMMON BRAND NAME(S): Mylicon

USES: This product is used to relieve symptoms of extra gas caused by air swallowing or certain foods/infant formulas. Simethicone helps break up gas bubbles in the gut.

HOW TO USE: If you are using the over-the-counter product to self-treat, read and follow all directions on the product package before using this medication. If your doctor has prescribed this medication, use it as directed.Give this product by mouth as needed, usually after meals and at bedtime, or as directed by the doctor. Follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.Shake the container well before each use. Carefully measure the dose using a special measuring device/dropper. Do not use a household spoon because you may not get the correct dose. Use the special measuring device/dropper to give the liquid by mouth. Try to give it slowly, aiming for the side of the inside cheek to prevent spitting or choking. The dosage may also be added to 1 ounce (30 milliliters) of cool water, infant formula, or juice. Mix well and give the liquid right away. If you are using a dropper to give this medication, rinse it well after each use.The dosage is based on your child's age and weight.If you are treating a child yourself (without direction from a doctor), do not use more than 12 doses of simethicone per day.If your child's condition lasts or gets worse, or if you think your child may have a serious medical problem, get medical help right away.

SIDE EFFECTS: Simethicone usually has very few side effects. If your child has any unusual effects from taking this product, tell your doctor or pharmacist promptly.If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before giving simethicone, tell your doctor or pharmacist if your child is allergic to it; or if your child has any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Simethicone can decrease the absorption of thyroid medications (such as levothyroxine). If you take thyroid medication, take it at least 4 hours before or after products that contain simethicone.

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

NOTES: Keep all regular medical and laboratory appointments.

MISSED DOSE: If your child is taking this product on a regular schedule and misses a dose, give it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Give the next dose at the regular time. Do not double the dose to catch up.

STORAGE: Store at room temperature away from moisture, heat, and light. Do not freeze. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised August 2021. Copyright(c) 2021 First Databank, Inc.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.