Dosing & Uses
Dosage Forms & Strengths
naphazoline/pheniramine
ophthalmic solution
- 0.025%/0.3%
- 0.027%/0.3%
Allergic Conjunctivitis
Instill 1-2 drops in affected eye(s) up to 4 times daily
Other Information
Remove contact lenses before using
Store at room temp; protect from light and excessive heat; use before expiration date
Dosage Forms & Strengths
naphazoline/pheniramine
ophthalmic solution
- 0.025%/0.3%
- 0.027%/0.3%
Allergic Conjunctivitis
<6 years: Not established
6 years or older: 1-2 drops in affected eye(s) up to 4 times daily
Other Information
Remove contact lenses before using
Store at room temp; protect from light and excessive heat; use before expiration date
Adverse Effects
Frequency Not Defined
Stinging/tingling sensation upon instillation
Mydriasis
Ocular erythema
Warnings
Contraindications
Hypersensitivity
Cautions
Cardiac disease
Hypertension
Benign prostatic hypertrophy
Narrow angle glaucoma
Pregnancy & Lactation
Pregnancy Category: C
Lactation: Unknown whether distributed in breast milk, weigh benefits against risks
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Absorption: Negligible systemic absorption
Mechanism of Action
Naphazoline: alpha-adrenergic agonist (decongestant)
Pheniramine: H1 blocker (antihistamine)
