triamcinolone, intranasal (OTC)

Brand and Other Names:Nasacort Allergy 24HR
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

nasal spray

  • 55mcg/spray
  • Note: Nasacort AQ (Rx) was phased out and replaced by Nasacort Allergy 24HR (OTC) in spring 2014

Allergic Rhinitis

2 sprays/nostril qDay (220 mcg/day); not to exceed 220 mcg/day

Dosing Considerations

Once maximum benefit has been achieved, reduce dose to 1 spray/nostril qDay (110 mcg/day) to minimize adverse effects while maintaining effectiveness

Administration

Suspension; shake well before use

Before using for first time, prime pump by releasing 5 sprays into air away from face

If not used for >2 weeks, repeat priming by releasing 1 spray into air before using

Dosage Forms & Strengths

nasal spray suspension

  • 55mcg/spray
  • Note: Nasacort AQ (Rx) was phased out and replaced by Nasacort Allergy 24HR (OTC) in spring 2014

Allergic Rhinitis

<2 years: Safety and efficacy not established

2-6 years: 1 spray/nostril qDay (110 mcg/day); not to exceed 110 mcg/day

6-12 years: 1 spray/nostril qDay; may increase to 2 sprays/nostril qDay (110 mcg/day); if inadequate response, may increase to 2 sprays/nostril qDay (ie, 220 mcg/day); not to exceed 220 mcg/day

≥12 years: 2 sprays/nostril qDay (220 mcg/day); not to exceed 220 mcg/day

Dosing Considerations

>6 years: Once maximum benefit has been achieved, reduce dose to 1 spray/nostril qDay (110 mcg/day) to minimize adverse effects while maintaining effectiveness

Administration

Suspension; shake well before use

Before using for first time, prime pump by releasing 5 sprays into air away from face

If not used for >2 weeks, repeat priming by releasing 1 spray into air before using

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Adverse Effects

1-10%

Flu syndrome [children] (9%)

Pharyngitis (5-8%)

Headache [children] (6%)

Bronchitis [children] (3%)

Dyspepsia (3-5%)

Tooth disorder [children] (3%)

Epistaxis (3-5%)

Excoriation [children] (3%)

Increased cough (2- 8%)

Upper abdominal pain [children] (5%)

Diarrhea [children] (3%)

Rash [children] (3%)

Asthma [children] (3%)

Rhinorrhea [children] (2%)

Postmarketing Experience

Nasal discomfort/congestion

Sneezing

Alterations of taste and smell

Nausea

Insomnia

Dizziness

Fatigue

Dyspnea

Decreased blood cortisol

Cataract

Glaucoma

Increased IOP

Pruritus

Rash

Hypersensitivity

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Warnings

Contraindications

Hypersensitivity

Cautions

Delay initiation of treatment in patients with recent nasal surgery, nasal trauma, nasal septum ulcers (until healing has occurred)

Prolonged use may increase incidence of secondary infection

Monitor for vision change, or with history of increased IOP, glaucoma, or cataracts

Potential worsening of existing tuberculosis, fungal, bacterial, viral, or parasitic infections, or ocular herpes simplex

More serious or fatal course of chickenpox or measles in susceptible patients

Risk for hypercorticism and adrenal suppression with higher than normal doses

Potential reduction of growth velocity in children

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Pregnancy & Lactation

Pregnancy Category: C

Lactation: Unknown whether distributed in breast milk; exercise caution

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Corticosteroid with potent anti-inflammatory properties; elicits effects on various cells, including mast cells and eosinophils; also elicits effects on inflammatory mediators (eg, histamine, eicosanoids, leukotrienes, cytokines)

Absorption

Minimal systemic absorption occurs, mostly by small amount swallowed during nasal administration

Distribution

Vd: 99.5 L

Peak plasma time: 1.5 hr

Peak plasma concentration: 0.5 ng/mL

Metabolism

Metabolites: 6β-hydroxytriamcinolone acetonide, 21-carboxytriamcinolone acetonide and 21-carboxy-6β-hydroxytriamcinolone acetonide (major)

Elimination

Half-life: 88 min

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Images

BRAND FORM. UNIT PRICE PILL IMAGE
Nasal Allergy nasal
-
55 mcg aerosol
Nasal Allergy nasal
-
55 mcg aerosol
triamcinolone acetonide injection
-
40 mg/mL vial
triamcinolone acetonide injection
-
40 mg/mL vial
triamcinolone acetonide injection
-
40 mg/mL vial
Kenalog topical
-
0.147 mg/gram aerosol
Kenalog topical
-
0.147 mg/gram aerosol
Nasacort nasal
-
55 mcg aerosol
Nasacort nasal
-
55 mcg aerosol
Nasacort nasal
-
55 mcg aerosol
Nasacort nasal
-
55 mcg aerosol
Trianex topical
-
0.05 % ointment
Kenalog injection
-
40 mg/mL vial
Kenalog injection
-
10 mg/mL vial
Kenalog injection
-
40 mg/mL vial
Kenalog injection
-
40 mg/mL vial
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % lotion
triamcinolone acetonide topical
-
0.147 mg/gram aerosol
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % lotion
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.5 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.025 % lotion
triamcinolone acetonide topical
-
0.1 % lotion
triamcinolone acetonide topical
-
0.1 % lotion
triamcinolone acetonide topical
-
0.1 % lotion
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.5 % ointment
triamcinolone acetonide topical
-
0.147 mg/gram aerosol
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.5 % cream
triamcinolone acetonide topical
-
0.5 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.5 % ointment
triamcinolone acetonide topical
-
0.147 mg/gram aerosol
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.5 % cream
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.5 % cream
triamcinolone acetonide topical
-
0.147 mg/gram aerosol
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % lotion
Oralone dental
-
0.1 % paste
triamcinolone acetonide dental
-
0.1 % paste
triamcinolone acetonide dental
-
0.1 % paste
triamcinolone acetonide dental
-
0.1 % paste
triamcinolone acetonide dental
-
0.1 % paste
triamcinolone acetonide dental
-
0.1 % paste
triamcinolone acetonide nasal
-
55 mcg aerosol
Zilretta intra-articular
-
32 mg vial
Kenalog-80 injection
-
80 mg/mL vial
Kenalog-80 injection
-
80 mg/mL vial

Copyright © 2010 First DataBank, Inc.

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Patient Education
triamcinolone acetonide injection

TRIAMCINOLONE - INJECTION

(trye-am-SIN-oh-lone AS-e-toe-nide)

COMMON BRAND NAME(S): Aristospan, Kenalog

USES: This medication is used in a variety of conditions such as allergic disorders, arthritis, gout, blood diseases, breathing problems, certain cancers, eye diseases, intestinal disorders, collagen and skin diseases. Talk to your doctor about the risks and benefits of triamcinolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use.Triamcinolone is known as a corticosteroid hormone (glucocorticoid). It works by decreasing your body's immune response to these diseases and reduces symptoms such as swelling.

HOW TO USE: Depending on your product, this medication may be given by injecting into different locations such as a muscle (intramuscularly), a skin lesion (intradermally), or a joint (intra-articularly). Injections are usually given by a trained healthcare professional. If you are giving yourself intramuscular injection, you will be taught by your healthcare professional on how to properly use this medication. If any of the information is unclear, consult your healthcare professional.The injection site, schedule, dosage, and length of treatment are based on your medical condition and response to treatment. Do not inject this medication into a vein (intravenously) or into the spine (epidurally). This medication is not recommended for injection around/into the eye or certain parts of the nose due to the risk for blindness or damage to the eye(s). Consult your doctor for more details.Use this medication and follow the dosing schedule exactly as directed by your doctor in order to get the most benefit from it. Do not change your dose or use this medication for a longer time than prescribed. Be sure to ask your doctor or pharmacist if you have any questions about your treatment.Wash hands with soap and water before using this medication. Before using, check this product visually for clumpy particles or discoloration. If either is present, do not use the liquid.Before injecting each dose intramuscularly, clean the injection site with rubbing alcohol. It is important to change the location of the injection site to avoid discomfort or problem areas. Your dose may need to be gradually decreased to reduce symptoms such as weakness, weight loss, nausea, and extreme fatigue.Shake vial before use to evenly disperse the suspension. Inject the prescribed dose immediately after withdrawing it into the syringe to avoid settling of the medication in the syringe.Learn how to store and discard syringes, needles, and medical supplies safely. Consult your pharmacist for more information.If you have been using this medication for a long time, do not suddenly stop it without your doctor's approval. Some conditions may become worse when this drug is suddenly stopped.This medication may be injected into a joint to treat conditions such as arthritis and bursitis. If you have received an injection into a joint, be careful how much stress you put on that joint, even if it is feeling better. Ask your doctor how much you can move the joint while it is healing.Tell your doctor if your condition gets worse or if you have new symptoms.

SIDE EFFECTS: Redness or pain at the injection site, stomach upset, headache, dizziness, trouble sleeping, or weight gain may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.This medication may make your blood sugar rise, which can cause or worsen diabetes. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. If you already have diabetes, check your blood sugar regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet.This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough).Tell your doctor right away if you have any serious side effects, including: weakness, puffy face, unusual weight gain, thinning skin, bone pain, menstrual period changes, mental/mood changes (such as depression, mood swings, agitation), easy bruising/bleeding, vision problems, swelling ankles/feet/hands, fast/slow/irregular heartbeat.If you have received injection of this medication into the joint, temporary discomfort of the joint may occur. Tell your doctor right away if you have fever, increased/severe pain with swelling of the joint, weakness in the joint, or decreased range of motion in the joint.Get medical help right away if you have any very serious side effects, including: symptoms of stomach/intestinal bleeding (such as stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds).A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using triamcinolone, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (such as methylprednisolone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, blood clots, bone loss (osteoporosis), diabetes, certain eye diseases (such as cataracts, glaucoma, herpes infection of the eye), heart problems (such as heart failure, recent heart attack), high blood pressure, current/past infections (such as joint infections and infections caused by fungus, herpes, tuberculosis, threadworm), kidney disease, liver disease, mental/mood conditions (such as psychosis, anxiety, depression), stomach/intestinal problems (such as diverticulitis, ulcer, ulcerative colitis), seizures, thyroid problems, mineral imbalance.This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).Using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. Before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication.This medication may mask signs of infection. It can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.Do not have immunizations, vaccinations, or skin tests without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).This medicine may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Limit alcoholic beverages.Older adults may be more sensitive to the side effects of this drug, especially bone loss/pain, stomach/intestinal bleeding, and mental/mood changes (such as confusion).This medication may slow down a child's growth if used for a long time. Consult the doctor or pharmacist for more details. See the doctor regularly so your child's height and growth can be checked.Injecting this medication into a muscle is not recommended for children younger than six years. Consult your doctor for more details.During pregnancy, this medication should be used only when clearly needed. It may rarely harm an unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who use corticosteroid medications for a long time may have hormone problems. Tell your doctor right away if you notice symptoms such as nausea/vomiting that doesn't stop, severe diarrhea, or weakness in your newborn.It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug are: aldesleukin, mifepristone, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen, "blood thinners" such as warfarin/dabigatran).Aspirin can increase the risk of bleeding when used with this medication. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually 81-162 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.This medication may interfere with certain lab tests (such as skin tests), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

NOTES: Do not share this medication with others. Lifestyle changes that help reduce the risk of bone loss (osteoporosis) during long-term therapy include weight-bearing exercise, getting adequate calcium and vitamin D, stopping smoking, and limiting alcohol. Discuss lifestyle changes that might benefit you with your doctor.Lab and/or medical tests (such as blood counts, blood glucose/mineral levels, blood pressure, bone density tests, height/weight measurements, eye exams, x-rays) should be done while you are using this medication. Keep all medical and lab appointments. Consult your doctor for more details.If you use this medication for prolonged periods, you should wear or carry identification stating that you are using it.

MISSED DOSE: This medication should be used as scheduled. If you miss a dose, contact your doctor or pharmacist for instructions. Do not double the dose to catch up.

STORAGE: Store at room temperature away from light and moisture. Do not freeze. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised August 2021. Copyright(c) 2021 First Databank, Inc.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.