triamcinolone, intranasal (OTC)

Brand and Other Names:Nasacort Allergy 24HR
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

nasal spray

  • 55mcg/spray
  • Note: Nasacort AQ (Rx) was phased out and replaced by Nasacort Allergy 24HR (OTC) in spring 2014

Allergic Rhinitis

2 sprays/nostril qDay (220 mcg/day); not to exceed 220 mcg/day

Dosing Considerations

Once maximum benefit has been achieved, reduce dose to 1 spray/nostril qDay (110 mcg/day) to minimize adverse effects while maintaining effectiveness

Administration

Suspension; shake well before use

Before using for first time, prime pump by releasing 5 sprays into air away from face

If not used for >2 weeks, repeat priming by releasing 1 spray into air before using

Dosage Forms & Strengths

nasal spray suspension

  • 55mcg/spray
  • Note: Nasacort AQ (Rx) was phased out and replaced by Nasacort Allergy 24HR (OTC) in spring 2014

Allergic Rhinitis

<2 years: Safety and efficacy not established

2-6 years: 1 spray/nostril qDay (110 mcg/day); not to exceed 110 mcg/day

6-12 years: 1 spray/nostril qDay; may increase to 2 sprays/nostril qDay (110 mcg/day); if inadequate response, may increase to 2 sprays/nostril qDay (ie, 220 mcg/day); not to exceed 220 mcg/day

≥12 years: 2 sprays/nostril qDay (220 mcg/day); not to exceed 220 mcg/day

Dosing Considerations

>6 years: Once maximum benefit has been achieved, reduce dose to 1 spray/nostril qDay (110 mcg/day) to minimize adverse effects while maintaining effectiveness

Administration

Suspension; shake well before use

Before using for first time, prime pump by releasing 5 sprays into air away from face

If not used for >2 weeks, repeat priming by releasing 1 spray into air before using

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Adverse Effects

1-10%

Flu syndrome [children] (9%)

Pharyngitis (5-8%)

Headache [children] (6%)

Bronchitis [children] (3%)

Dyspepsia (3-5%)

Tooth disorder [children] (3%)

Epistaxis (3-5%)

Excoriation [children] (3%)

Increased cough (2- 8%)

Upper abdominal pain [children] (5%)

Diarrhea [children] (3%)

Rash [children] (3%)

Asthma [children] (3%)

Rhinorrhea [children] (2%)

Postmarketing Experience

Nasal discomfort/congestion

Sneezing

Alterations of taste and smell

Nausea

Insomnia

Dizziness

Fatigue

Dyspnea

Decreased blood cortisol

Cataract

Glaucoma

Increased IOP

Pruritus

Rash

Hypersensitivity

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Warnings

Contraindications

Hypersensitivity

Cautions

Delay initiation of treatment in patients with recent nasal surgery, nasal trauma, nasal septum ulcers (until healing has occurred)

Prolonged use may increase incidence of secondary infection

Monitor for vision change, or with history of increased IOP, glaucoma, or cataracts

Potential worsening of existing tuberculosis, fungal, bacterial, viral, or parasitic infections, or ocular herpes simplex

More serious or fatal course of chickenpox or measles in susceptible patients

Risk for hypercorticism and adrenal suppression with higher than normal doses

Potential reduction of growth velocity in children

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Pregnancy & Lactation

Pregnancy Category: C

Lactation: Unknown whether distributed in breast milk; exercise caution

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Corticosteroid with potent anti-inflammatory properties; elicits effects on various cells, including mast cells and eosinophils; also elicits effects on inflammatory mediators (eg, histamine, eicosanoids, leukotrienes, cytokines)

Absorption

Minimal systemic absorption occurs, mostly by small amount swallowed during nasal administration

Distribution

Vd: 99.5 L

Peak plasma time: 1.5 hr

Peak plasma concentration: 0.5 ng/mL

Metabolism

Metabolites: 6β-hydroxytriamcinolone acetonide, 21-carboxytriamcinolone acetonide and 21-carboxy-6β-hydroxytriamcinolone acetonide (major)

Elimination

Half-life: 88 min

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Images

BRAND FORM. UNIT PRICE PILL IMAGE
Nasacort nasal
-
55 mcg aerosol
Nasacort nasal
-
55 mcg aerosol
Nasacort nasal
-
55 mcg aerosol
Nasacort nasal
-
55 mcg aerosol
Kenalog-80 injection
-
80 mg/mL vial
Kenalog-80 injection
-
80 mg/mL vial
Zilretta intra-articular
-
32 mg vial
triamcinolone acetonide nasal
-
55 mcg aerosol
triamcinolone acetonide dental
-
0.1 % paste
triamcinolone acetonide dental
-
0.1 % paste
triamcinolone acetonide dental
-
0.1 % paste
triamcinolone acetonide dental
-
0.1 % paste
triamcinolone acetonide dental
-
0.1 % paste
Oralone dental
-
0.1 % paste
Trianex topical
-
0.05 % ointment
Nasal Allergy nasal
-
55 mcg aerosol
Nasal Allergy nasal
-
55 mcg aerosol
triamcinolone acetonide injection
-
40 mg/mL vial
triamcinolone acetonide injection
-
40 mg/mL vial
triamcinolone acetonide injection
-
40 mg/mL vial
Kenalog topical
-
0.147 mg/gram aerosol
Kenalog topical
-
0.147 mg/gram aerosol
Kenalog injection
-
10 mg/mL vial
Kenalog injection
-
40 mg/mL vial
Kenalog injection
-
40 mg/mL vial
Kenalog injection
-
40 mg/mL vial
triamcinolone acetonide topical
-
0.1 % lotion
triamcinolone acetonide topical
-
0.1 % lotion
triamcinolone acetonide topical
-
0.025 % lotion
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.147 mg/gram aerosol
triamcinolone acetonide topical
-
0.147 mg/gram aerosol
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % lotion
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.5 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.5 % ointment
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.5 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.5 % ointment
triamcinolone acetonide topical
-
0.147 mg/gram aerosol
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.5 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.147 mg/gram aerosol
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.025 % ointment
triamcinolone acetonide topical
-
0.5 % ointment
triamcinolone acetonide topical
-
0.1 % lotion
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.5 % cream
triamcinolone acetonide topical
-
0.025 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % lotion
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % ointment
triamcinolone acetonide topical
-
0.1 % cream
triamcinolone acetonide topical
-
0.1 % cream

Copyright © 2010 First DataBank, Inc.

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Patient Education
triamcinolone acetonide nasal

TRIAMCINOLONE ACETONIDE - NASAL

(tri-am-SIN-oh-lone uh-SET-oh-nide)

COMMON BRAND NAME(S): Nasacort

USES: Triamcinolone is used to prevent and treat seasonal and year-round allergy symptoms (such as stuffy/runny nose, itchy eyes/nose/throat, sneezing). Triamcinolone belongs to a class of drugs known as corticosteroids. It works by reducing swelling (inflammation) in the nasal passages.Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.

HOW TO USE: If you are taking the over-the-counter product to self-treat, read and follow all directions on the product package before taking this medication. If you have any questions, consult your pharmacist. If your doctor has prescribed this medication, take it as directed.Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. Follow the illustrated directions for the proper use of this medication. If you have any questions, ask your doctor or pharmacist.This medication is for use in the nose. In adults, the usual dose is 2 sprays in each nostril once or twice a day or as directed by your doctor. In children, the usual dose is 1 to 2 sprays in each nostril once daily or as directed by the doctor. Avoid spraying this medication in your eyes or mouth. Gently blow your nose before using this drug. Shake the spray device well before each use. Follow the package instructions to properly prime the spray.Remove the protective cap before using the spray. Close one nostril by pressing it with your finger. Tilt your head as directed and carefully insert the nasal applicator into the other nostril. Press down firmly on the device to deliver the prescribed number of sprays. Do not spray directly onto the middle wall of your nose (nasal septum). Breathe in gently through your nose and out through your mouth. Repeat in the other nostril. Replace the cap on the nasal inhaler. Avoid blowing your nose for 15 minutes after using this medication.Dosage is based on your medical condition and response to treatment. Younger children may need a smaller dose and help from an adult to use this medication properly. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time(s) each day. Do not increase your dose or use it more frequently than directed.This medication does not work right away. Some people will feel this medication working within 1 day, but it may take up to 1 week before the full benefit of this drug takes effect. Ask your doctor or pharmacist if you should also use other medications (such as nose drops/spray, allergy drugs taken by mouth) along with this drug until it takes full effect.Keep track of the number of sprays used from the device. Discard the device after you have used the number of sprays specified on the manufacturer's package. Do not pour any remaining medication into another container. Follow the package instructions to unblock or to clean the spray device.If your condition lasts or gets worse, or if you think you may have a serious medical problem, get medical help right away.

SIDE EFFECTS: Nose/throat dryness or irritation, cough, sneezing, nosebleeds, and unpleasant taste/smell may occur. If any of these side effects last or get worse, tell your doctor or pharmacist promptly.If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: loss of taste or smell, pain/sores in your nose.Rarely, it is possible that corticosteroids given in the nose will be absorbed into the bloodstream. This can lead to side effects of too much corticosteroid. These side effects are more likely in children and people who use this medication for a long time and in high doses. Tell your doctor right away if any of the following side effects occur: unusual/extreme tiredness, weight loss, headache, swelling ankles/feet, increased thirst/urination, vision problems.Corticosteroids may weaken the body's ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. This effect might also rarely occur with corticosteroids inhaled through the nose (such as triamcinolone). The risk may be increased if high doses are used, especially when used for a long time. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, ear pain, fever, chills, white patches inside the nose or on the back of the throat).A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, wheezing/trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using nasal triamcinolone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye problems (such as glaucoma, cataracts), infections (including tuberculosis), recent nose problems (such as injury, ulcers, surgery).Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.Rarely, using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. Before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past few months.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Though it is unlikely, this medication may temporarily slow down a child's growth if used for a long time. See the doctor regularly so your child's height can be checked.During pregnancy, this medication should be used only when clearly needed. Rarely, infants born to mothers who have been using corticosteroids (including triamcinolone) for a long time may have low levels of corticosteroid hormone. Tell your doctor right away if you notice symptoms such as nausea/vomiting that doesn't stop, severe diarrhea, or weakness in your newborn. Discuss the risks and benefits with your doctor.It is unknown if this drug passes into breast milk. However, similar drugs pass into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Check all prescription medicine labels carefully since similar medications (other corticosteroids such as prednisone) may increase your risk of side effects if taken together with this drug. Ask your doctor or pharmacist if you have any questions about your medications.

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

NOTES: Keep all regular medical and laboratory appointments.Do not share this medication with others.If you use this medication for a long time, laboratory and/or medical tests (such as nose exams, height measurement in children) may be performed to monitor your progress and check for side effects.Avoid substances (such as pollen, pet dander, dust mites, mold, and smoke) that can worsen allergy symptoms.

MISSED DOSE: If you are using this product on a regular schedule and miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised April 2022. Copyright(c) 2022 First Databank, Inc.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.