Dosing & Uses
Dosage Forms & Strengths
ophthalmic suspension
- 5%
Fungal Keratitis
1 gtt in conjunctival sac q1-2hr
May decrease to 1 gtt 6-8 times/day after 3-4 days
Continue for 14-21 days until infection eradicated
Fungal Blepharitis/Conjunctivitis
1 gtt in conjunctival sac 4-6 times/day
Other Indications & Uses
Off-label: Candidiasis
Safety & efficacy not established
Adverse Effects
Frequency Not Defined
Eye irritation
Warnings
Contraindications
Hypersensitivity
Concurrent use with topical corticosteroid
Cautions
For keratitis, consider alternative tx if no improvement in 7-10 d
Pregnancy & Lactation
Pregnancy Category: C
Lactation: no problems reported
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Macrolide antifungal antibiotic, binds to sterols in the fungal cell membrane & renders it nonfunctional
Images
Patient Handout
Formulary
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all your plans together – even plans in different states.
- Compare formulary status to other drugs in the same class.
- Access your plan list on any device – mobile or desktop.
