neomycin/polymyxin B/bacitracin topical (OTC)

Brand and Other Names:Neosporin Original Ointment, Triple Antibiotic Ointment
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Dosing & Uses

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Dosage Forms & Strengths

neomycin/polymyxin B/bacitracin topical

topical cream/ointment

  • (3.5mg/5,000units/400units)/1gram

Treatment/Prophylaxis Superficial Skin Infection

Apply topically qDay-TID

Also known as triple antibiotic cream/ointment

Dosage Forms & Strengths

neomycin/polymyxin B/bacitracin topical

topical cream/ointment

  • (3.5mg/5,000units/400units)/1gram

Treatment/Prophylaxis Superficial Skin Infection

Apply topically qDay-TID

Also known as triple antibiotic cream/ointment

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Interactions

Interaction Checker

and neomycin/polymyxin B/bacitracin topical

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            >10%

            Allergic contact dermatitis (60%)

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            Warnings

            Contraindications

            Hypersensitivity

            Not for use in eyes or over large areas of body

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: unknown if distributed in breast milk

            Pregnancy Categories

            A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA: Information not available.

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            Pharmacology

            Mechanism of Action

            Neomycin: Antibiotic; inhibits production of protine in bacteria resulting in cell death

            Polymyxin: Antibiotic; increases permeability of bacterial cell wall membranes resulting in cell lysis

            Bacitracin: Antibiotic; bactericidal or bacteriostatic depending on concetnraiton; inhibits bacterial cell wall synthesis

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            Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.