nystatin topical (Rx)

Brand and Other Names:Mycostatin topical, Pediaderm AF, more...PediDri, Nystop
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

cream/ointment/powder

  • 100,000 units/g

Mucocutaneous Infection

Apply to affected area q8-12hr until healing is complete or as indicated

See also combo with triamcinolone

Vaginal Infections

Insert 1 tablet/day qHS until healing is complete or as indicated

Dosage Forms & Strengths

cream/ointment/powder

  • 100,000 units/g

Mucocutaneous Infection

Apply to affected area q8-12hr until healing is complete or as indicated

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Adverse Effects

Frequency Not Defined

Nontoxic; well tolerated by all age groups

Contact dermatitis

Stevens-Johnson syndrome

Acneiform eruption (rare)

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Warnings

Contraindications

Hypersensitivity

Cautions

Discontinue immediately if signs of hypersensitivity reaction occur

Discontinue if irritation occurs at application site

For external use only; not for systemic, oral, intravaginal, or ophthalmic use

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Pregnancy & Lactation

Pregnancy category: C

Lactation: Not known whether excreted in breast milk; absorption following oral use is poor; manufacturer advices caution when administering to nursing women

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Binds to fungal cell membrane sterols; as a result, the membrane no longer functions as a selective barrier, and potassium and other cellular constituents are lost

Absorption

Not from intact skin or mucous membrane

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Administration

Topical Administration

Cream preferred to ointment in candidiasis involving intertriginous areas

Moist lesions best treated with powder

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Images

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Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.