Dosing & Uses
Dosage Forms & Strengths
cream/ointment/powder
- 100,000 units/g
Mucocutaneous Infection
Apply to affected area q8-12hr until healing is complete or as indicated
See also combo with triamcinolone
Vaginal Infections
Insert 1 tablet/day qHS until healing is complete or as indicated
Dosage Forms & Strengths
cream/ointment/powder
- 100,000 units/g
Mucocutaneous Infection
Apply to affected area q8-12hr until healing is complete or as indicated
Adverse Effects
Frequency Not Defined
Nontoxic; well tolerated by all age groups
Contact dermatitis
Stevens-Johnson syndrome
Acneiform eruption (rare)
Warnings
Contraindications
Hypersensitivity
Cautions
Discontinue immediately if signs of hypersensitivity reaction occur
Discontinue if irritation occurs at application site
For external use only; not for systemic, oral, intravaginal, or ophthalmic use
Pregnancy & Lactation
Pregnancy category: C
Lactation: Not known whether excreted in breast milk; absorption following oral use is poor; manufacturer advices caution when administering to nursing women
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Binds to fungal cell membrane sterols; as a result, the membrane no longer functions as a selective barrier, and potassium and other cellular constituents are lost
Absorption
Not from intact skin or mucous membrane
Administration
Topical Administration
Cream preferred to ointment in candidiasis involving intertriginous areas
Moist lesions best treated with powder
Images
Patient Handout
Formulary
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all your plans together – even plans in different states.
- Compare formulary status to other drugs in the same class.
- Access your plan list on any device – mobile or desktop.
