Suggested Dosing
Exercise Endurance
1 mg PO qDay
Cholesterol Lowering
10-20 mg PO qDay
Parkinson's Disease
5 mg PO TID with meals
Amytrophic Lateral Sclerosis (ALS)
40 mg PO qDay
Suggested Uses
Enhance physical endurance
Lower cholesterol & increase HDL
Parkinson's Disease
ALS
Efficacy
Small clinical studies suggest some benefit regarding endurance & Parkinson's Disease
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Contraindicated (0)
Serious - Use Alternative (0)
Monitor Closely (0)
Minor (72)
- acebutolol
octacosanol increases effects of acebutolol by pharmacodynamic synergism. Minor/Significance Unknown.
- amiloride
octacosanol increases effects of amiloride by pharmacodynamic synergism. Minor/Significance Unknown.
- amlodipine
octacosanol increases effects of amlodipine by pharmacodynamic synergism. Minor/Significance Unknown.
- atenolol
octacosanol increases effects of atenolol by pharmacodynamic synergism. Minor/Significance Unknown.
- bendroflumethiazide
octacosanol increases effects of bendroflumethiazide by pharmacodynamic synergism. Minor/Significance Unknown.
- betaxolol
octacosanol increases effects of betaxolol by pharmacodynamic synergism. Minor/Significance Unknown.
- bisoprolol
octacosanol increases effects of bisoprolol by pharmacodynamic synergism. Minor/Significance Unknown.
- bosentan
octacosanol increases effects of bosentan by pharmacodynamic synergism. Minor/Significance Unknown.
- bumetanide
octacosanol increases effects of bumetanide by pharmacodynamic synergism. Minor/Significance Unknown.
- candesartan
octacosanol increases effects of candesartan by pharmacodynamic synergism. Minor/Significance Unknown.
- carvedilol
octacosanol increases effects of carvedilol by pharmacodynamic synergism. Minor/Significance Unknown.
- celiprolol
octacosanol increases effects of celiprolol by pharmacodynamic synergism. Minor/Significance Unknown.
- chlorothiazide
octacosanol increases effects of chlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.
- chlorthalidone
octacosanol increases effects of chlorthalidone by pharmacodynamic synergism. Minor/Significance Unknown.
- ciprofibrate
octacosanol increases effects of ciprofibrate by pharmacodynamic synergism. Minor/Significance Unknown.
- clevidipine
octacosanol increases effects of clevidipine by pharmacodynamic synergism. Minor/Significance Unknown.
- clonidine
octacosanol increases effects of clonidine by pharmacodynamic synergism. Minor/Significance Unknown.
- cyclopenthiazide
octacosanol increases effects of cyclopenthiazide by pharmacodynamic synergism. Minor/Significance Unknown.
- diltiazem
octacosanol increases effects of diltiazem by pharmacodynamic synergism. Minor/Significance Unknown.
- drospirenone
octacosanol increases effects of drospirenone by pharmacodynamic synergism. Minor/Significance Unknown.
- enalapril
octacosanol increases effects of enalapril by pharmacodynamic synergism. Minor/Significance Unknown.
- eplerenone
octacosanol increases effects of eplerenone by pharmacodynamic synergism. Minor/Significance Unknown.
- eprosartan
octacosanol increases effects of eprosartan by pharmacodynamic synergism. Minor/Significance Unknown.
- esmolol
octacosanol increases effects of esmolol by pharmacodynamic synergism. Minor/Significance Unknown.
- ethacrynic acid
octacosanol increases effects of ethacrynic acid by pharmacodynamic synergism. Minor/Significance Unknown.
- felodipine
octacosanol increases effects of felodipine by pharmacodynamic synergism. Minor/Significance Unknown.
- fenofibrate
octacosanol increases effects of fenofibrate by pharmacodynamic synergism. Minor/Significance Unknown.
- fenofibrate micronized
octacosanol increases effects of fenofibrate micronized by pharmacodynamic synergism. Minor/Significance Unknown.
- fenofibric acid
octacosanol increases effects of fenofibric acid by pharmacodynamic synergism. Minor/Significance Unknown.
- fosinopril
octacosanol increases effects of fosinopril by pharmacodynamic synergism. Minor/Significance Unknown.
- furosemide
octacosanol increases effects of furosemide by pharmacodynamic synergism. Minor/Significance Unknown.
- gemfibrozil
octacosanol increases effects of gemfibrozil by pharmacodynamic synergism. Minor/Significance Unknown.
- guanfacine
octacosanol increases effects of guanfacine by pharmacodynamic synergism. Minor/Significance Unknown.
- hydrochlorothiazide
octacosanol increases effects of hydrochlorothiazide by pharmacodynamic synergism. Minor/Significance Unknown.
- iloprost
octacosanol increases effects of iloprost by pharmacodynamic synergism. Minor/Significance Unknown.
- imidapril
octacosanol increases effects of imidapril by pharmacodynamic synergism. Minor/Significance Unknown.
- indapamide
octacosanol increases effects of indapamide by pharmacodynamic synergism. Minor/Significance Unknown.
- irbesartan
octacosanol increases effects of irbesartan by pharmacodynamic synergism. Minor/Significance Unknown.
- isradipine
octacosanol increases effects of isradipine by pharmacodynamic synergism. Minor/Significance Unknown.
- ketanserin
octacosanol increases effects of ketanserin by pharmacodynamic synergism. Minor/Significance Unknown.
- labetalol
octacosanol increases effects of labetalol by pharmacodynamic synergism. Minor/Significance Unknown.
- lisinopril
octacosanol increases effects of lisinopril by pharmacodynamic synergism. Minor/Significance Unknown.
- losartan
octacosanol increases effects of losartan by pharmacodynamic synergism. Minor/Significance Unknown.
- mecamylamine
octacosanol increases effects of mecamylamine by pharmacodynamic synergism. Minor/Significance Unknown.
- methyclothiazide
octacosanol increases effects of methyclothiazide by pharmacodynamic synergism. Minor/Significance Unknown.
- metolazone
octacosanol increases effects of metolazone by pharmacodynamic synergism. Minor/Significance Unknown.
- metoprolol
octacosanol increases effects of metoprolol by pharmacodynamic synergism. Minor/Significance Unknown.
- metyrosine
octacosanol increases effects of metyrosine by pharmacodynamic synergism. Minor/Significance Unknown.
- moexipril
octacosanol increases effects of moexipril by pharmacodynamic synergism. Minor/Significance Unknown.
- moxonidine
octacosanol increases effects of moxonidine by pharmacodynamic synergism. Minor/Significance Unknown.
- nadolol
octacosanol increases effects of nadolol by pharmacodynamic synergism. Minor/Significance Unknown.
- nebivolol
octacosanol increases effects of nebivolol by pharmacodynamic synergism. Minor/Significance Unknown.
- nicardipine
octacosanol increases effects of nicardipine by pharmacodynamic synergism. Minor/Significance Unknown.
- nifedipine
octacosanol increases effects of nifedipine by pharmacodynamic synergism. Minor/Significance Unknown.
- nisoldipine
octacosanol increases effects of nisoldipine by pharmacodynamic synergism. Minor/Significance Unknown.
- olmesartan
octacosanol increases effects of olmesartan by pharmacodynamic synergism. Minor/Significance Unknown.
- penbutolol
octacosanol increases effects of penbutolol by pharmacodynamic synergism. Minor/Significance Unknown.
- perindopril
octacosanol increases effects of perindopril by pharmacodynamic synergism. Minor/Significance Unknown.
- pindolol
octacosanol increases effects of pindolol by pharmacodynamic synergism. Minor/Significance Unknown.
- propranolol
octacosanol increases effects of propranolol by pharmacodynamic synergism. Minor/Significance Unknown.
- quinapril
octacosanol increases effects of quinapril by pharmacodynamic synergism. Minor/Significance Unknown.
- ramipril
octacosanol increases effects of ramipril by pharmacodynamic synergism. Minor/Significance Unknown.
- sacubitril/valsartan
octacosanol increases effects of sacubitril/valsartan by pharmacodynamic synergism. Minor/Significance Unknown.
- sotalol
octacosanol increases effects of sotalol by pharmacodynamic synergism. Minor/Significance Unknown.
- spironolactone
octacosanol increases effects of spironolactone by pharmacodynamic synergism. Minor/Significance Unknown.
- telmisartan
octacosanol increases effects of telmisartan by pharmacodynamic synergism. Minor/Significance Unknown.
- timolol
octacosanol increases effects of timolol by pharmacodynamic synergism. Minor/Significance Unknown.
- torsemide
octacosanol increases effects of torsemide by pharmacodynamic synergism. Minor/Significance Unknown.
- trandolapril
octacosanol increases effects of trandolapril by pharmacodynamic synergism. Minor/Significance Unknown.
- triamterene
octacosanol increases effects of triamterene by pharmacodynamic synergism. Minor/Significance Unknown.
- valsartan
octacosanol increases effects of valsartan by pharmacodynamic synergism. Minor/Significance Unknown.
- verapamil
octacosanol increases effects of verapamil by pharmacodynamic synergism. Minor/Significance Unknown.
Adverse Effects
None reported
Warnings
None
Pregnancy & Lactation
Pregnancy Category: N/A
Lactation: N/A
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Absorption: low
Metabolism: N/A
Excretion: feces, metabolites in urine
Mechanism of Action
Long chain aliphatic alcohol; may improve oxygen utilization by muscle cells, lower lactic acid accumulation during exercise
