Dosing & Uses
AdultPediatric
Dosage Forms & Strengths
Large number of products available; consult each product labeling
Age-Related Macular Degeneration
In a National Eye Institute’s age-related eye study (AREDS) results showed a reduction in risk of 25% for developing advanced AMD and a 19% reduction in the risk of vision loss among moderate to advanced AMD patients
PreserVision Eye Vitamin AREDS 2 Formula Soft Gels
- [capsule]: zinc 40 mg; vitamin C 250 mg; vitamin E 90 mg; lutein 5 mg; zeaxanthin 1 mg (replaces beta-carotene); copper 1 mg
- 1 capsule PO twice daily with morning and evening meals
PreserVision Eye Vitamin AREDS 2 Formula Soft Gels plus CoQ10
- [capsule]: zinc 40 mg; vitamin C 250 mg; vitamin E 90 mg; lutein 5 mg; zeaxanthin 1 mg (replaces beta-carotene); copper 1 mg; coenzyme Q10 50 mg
- 1 capsule PO twice daily with morning and evening meals
PreserVision Eye Vitamin AREDS Formula Soft Gels
- [capsule]: zinc 34.8 mg; vitamin A (as beta-carotene) 4,296 mcg; vitamin C 226 mg; vitamin E 90 mg; copper 0.8 mg
- 1 capsule PO twice daily with morning and evening meals
PreserVision Eye Vitamin AREDS Formula Tablets
- [tablet]: zinc 17.4 mg; vitamin A (as beta carotene) 2,148 mcg; vitamin C 113 mg; vitamin E 90 mg; copper 0.4 mg
- 2 tablets PO twice daily with morning and evening meals
PreserVision Eye Vitamin Lutein Formula Soft Gels
- [capsule]: zinc 34.8 mg; vitamin C 226 mg; vitamin E 90 mg; copper 0.8 mg; lutein 5 mg
- 1 capsule PO twice daily with morning and evening meals
ICAPS Eye Vitamin AREDS Formula
- [soft-gel cap]: zinc 17.4 mg; vitamin A 7,160 IU; vitamin C 113 mg; vitamin E 100 IU; copper 0.4 mg
- 2 capsules PO twice daily with morning and evening meals
Ocular Vitamin Supplementation
Ocuvite Adult 50+ Age-adjusted Formula
- [capsule]: zinc 9 mg; vitamin C 150 mg; vitamin E 30 IU; copper 1 mg; lutein 6 mg; omega-3 150 mg
- 1 capsule qDay, in morning taken with food
- Do not exceed the dose indicated without seeking medical advice
Ocuvite Eye Vitamins & Mineral Supplements
- [tablet]: zinc 40 mg; vitamin A 1,000 IU; vitamin C 200 mg; vitamin E 60 IU; copper 2 mg; selenium 55 mcg; lutein 2 mg
- 1 tablet qDay or twice daily as directed by physician
Ocuvite Lutein Eye Vitamins
- [capsule] zinc 15 mg; vitamin C 60 mg; vitamin E 30 IU; copper 2 mg; lutein 6 mg
- 1 capsule qDay or twice daily as directed by physician
ICAPS Eye Vitamin Lutein & Omega-3 Vitamin
- [soft-gel cap]: vitamin A 600 mcg; vitamin C 45 mg; vitamin E 10 IU; thiamine 1.2 mg; riboflavin 1.3 mg; niacin 16 mg; vitamin B6 1.3 mg; folic acid 250 mcg; vitamin B12 2.4 mcg; calcium 1 mg; zinc 7 mg; selenium 34 mcg; copper 0.9 mg; manganese 2.3 mg; lutein 10 mg; zeaxanthin 2 mg; omega-3 fatty acids 280 mg
- 1 tablet PO qDay with a meal
ICAPS Eye Vitamin Lutein & Zeaxanthin Formula
- [tablet]: vitamin A 3,300 IU; vitamin C 200 mg; vitamin E (dt-alpha tocopheryl acetate) 75 IU; riboflavin 5 mg; zinc 30 mg; copper 4 mg; manganese 5 mg; selenium 20 mcg; lutein/zeaxanthin 2 mg; calcium 20 mg
- 2 tablets PO qDay with a meal
ICAPS Eye Vitamin Multivitamin Formula
- [tablet]: vitamin C 128 mg; vitamin D 100 IU; vitamin E 107.5 IU; vitamin K 7.25 mcg; thiamin 0.375 mg; riboflavin 2.5 mg; niacin 2.5 mg; vitamin B6 0.5 mg; folic acid 100 mcg; vitamin B12 1.5 mcg; biotin 7.5 mcg; pantothenic acid 2.5 mg; calcium 82.5 mg; phosphorus 35 mg; iodine 37.5 mcg; magnesium 25 mg; zinc 21.15 mg; selenium 10 mcg; copper 0.9 mg; manganese 0.5 mg; chromium 30 mcg; molybdenum 18.75 mcg; potassium 20 mg; lutein 1.66 mg; zeaxanthin 0.83 mg; lycopene 0.075 mg
- 2 tablets PO twice daily with meals
Safety and efficacy not established
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Adverse Effects
Frequency Not Defined
Nausea
GI distress
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Warnings
Contraindications
Hypersensitivity
Cautions
Avoid high doses of beta-carotene in individuals who smoke; associated with increased risk of lung cancer in males and tobacco-related cancers in women
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Pregnancy & Lactation
Pregnancy Category: C
Lactation: distributed in breast milk, caution advised
These vitamins are not intended for pregnancy or breastfeeding
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Previous
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Pharmacology
Mechanism of Action
Antioxidant vitamins and minerals
- Strategies to prevent the conversion from dry AMD to wet AMD include high-dose consumption of the antioxidant vitamins, C, E, and beta-carotene, plus the minerals zinc and copper
- Over a 10-year period, researchers conducting a trial sponsored by the Age-related Eye Disease Study (AREDS) Research Group observed a significant reduction in the development of wet AMD in at-risk individuals who used the Ocuvite PreserVision preparation containing vitamins A, C, and E as well as zinc and copper compared with those who took antioxidants alone, zinc plus copper, or placebo
- Lutein, omega-3 fatty acids, and zeaxanthin may also provide risk reduction for AMD
- Lutein, a carotenoid found in dark leafy green vegetables, is currently being evaluated in the AREDS-2 trial
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Images
No images available for this drug.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
