Dosing & Uses
Schizophrenia
Pending FDA approval for schizophrenia
Bipolar 1 Disorder
Pending FDA approval for bipolar I disorder
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Pharmacology
Mechanism of Action
Olanzapine: May act through combination of dopamine and serotonin type 2 receptor site antagonism
Samidorphan: Opioid antagonist; mitigates weight gain associated with olanzapine
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Patient Handout
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
