oliceridine (Pending FDA Approval)

Brand and Other Names:Olinvo
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Dosing & Uses

Acute Pain

Pending FDA approval for moderate-to-severe acute pain where IV therapy is preferred

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Pharmacology

Mechanism of Action

Mu-opioid receptor biased agonist that elicits G protein signaling, with similar potency and efficacy to morphine, but with much less beta-arrestin 2 recruitment and receptor internalization, which may result in fewer adverse effects

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.