Dosing & Uses
Spasticity
Pending FDA approval for treatment of spasticity in patients with multiple sclerosis (MS)
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Pharmacology
Mechanism of Action
Prodrug that is converted R-enantiomer of baclofen; allows for oral dosing with higher bioavailability
Inhibits synaptic transmission through spinal reflex arcs via hyperpolarization of primary afferent fiber terminals; this inhibition may decrease in muscle spasticity
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Images
No images available for this drug.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
