Oxistat (oxiconazole) dosing, indications, interactions, adverse effects, and more

Sections

Sections oxiconazole
Dosing & Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology
Images
Patient Handout
Formulary

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

cream/lotion

Fungal Infections

Apply qDay-BID to affected & surrounding area

Tinea pedis: x4 weeks

Tinea cruris & corporis: x2 weeks

Dosage Forms & Strengths

cream/lotion

Fungal Infections

Apply qDay-BID to affected & surrounding area

These infections rarely occur in <12 years old

Interaction Checker

Enter a drug name and oxiconazole

No Results

No Interactions Found

Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

All Interactions Sort By:

1-10%

Pruritus (1-2%)

Burning (1-2%)

<1%

Irritation

Stinging

Erythema

Rash

Folliculitis

Papules

Nodules

Maceration

Fissuring

Contraindications

Hypersensitivity

Not for ophthalmic or intravaginal use

Pregnancy & Lactation

Pregnancy Category: B

Lactation: distributed into milk; use with caution in nursing women

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Absorption: minimal

Excretion: urine (0.3%) within 5 days

Enzymes inhibited: hepatic CYP3A4

Mechanism of Action

Fungistatic in action but may be fungicidal in high concentrations or against very susceptible organisms

Presumably exerts its antifungal activity by altering cellular membranes, resulting in increased membrane permeability, secondary metabolic effects, and growth inhibition

Appears that the antifungal activity of the drug results from interference with ergosterol synthesis, probably via inhibition of C-14 methylation of sterol intermediates (e.g., lanosterol)

Images

Patient Handout

Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Create Your List of Plans

Adding plans allows you to:

View the formulary and any restrictions for each plan.
Manage and view all your plans together – even plans in different states.
Compare formulary status to other drugs in the same class.
Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

View explanations for tiers and restrictions

Tier	Description
1	This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2	This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC	NOT COVERED – Drugs that are not covered by the plan.

Code	Definition
PA	Prior Authorization Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL	Quantity Limits Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST	Step Therapy Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR	Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

[CLOSE WINDOW]

Sections oxiconazole
Dosing & Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology
Images
Patient Handout
Formulary

oxiconazole (Rx)

Dosing & Uses

Dosage Forms & Strengths

cream/lotion

Fungal Infections

Dosage Forms & Strengths

cream/lotion

Fungal Infections

Interactions

Interaction Checker

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

Adverse Effects

1-10%

<1%

Warnings

Contraindications

Pregnancy & Lactation

Pregnancy Categories

Pharmacology

Mechanism of Action

Images

Patient Handout

Formulary

Plans

What would you like to print?

Dosing Calculator