Dosing & Uses
Dosing Strengths & Forms
capsule
- 60mg
- 500mg
tablet
- 500mg
powder
- 2g
Supplement
12 g PO divided q4-6hr
Administration
Take with adequate liquid to avoid gastric upset
Dosing Strengths & Forms
capsule
- 60mg
- 500mg
tablet
- 500mg
powder
- 2g
Supplement
1g/10 pounds of weight/day PO in divided doses
Interactions
Interaction Checker
No Results

Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor

Contraindicated (0)
Serious - Use Alternative (3)
- sulfadiazine
aminobenzoate potassium decreases effects of sulfadiazine by pharmacodynamic antagonism. Avoid or Use Alternate Drug.
- sulfamethoxazole
aminobenzoate potassium decreases effects of sulfamethoxazole by pharmacodynamic antagonism. Avoid or Use Alternate Drug.
- sulfisoxazole
aminobenzoate potassium decreases effects of sulfisoxazole by pharmacodynamic antagonism. Avoid or Use Alternate Drug.
Monitor Closely (1)
- omadacycline
aminobenzoate potassium will decrease the level or effect of omadacycline by inhibition of GI absorption. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Separate dosing of tetracyclines from these products.
Minor (0)
Adverse Effects
Frequency Not Defined
Anorexia
Nausea
Fever
Hepatotoxicity
Rash
Warnings
Contraindications
Hypersensitivity
Concomitant sulfonamide antibiotics (effects may be nullified)
Cautions
Stop therapy if anorexia occurs and reinitiate therapy once appetite improves
Stop therapy if nausea occurs and reinitiate therapy once patient improves
Use wiht caution in diabetes mellitus, hypoglycemia, or renal disease
Pregnancy & Lactation
Pregnancy Category: Not studied
Lactation: Unknown if excreted in breast milk; use caution
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Related to B vitamins that may have antifibrotic effects by increasing oxygen uptake at tissues level
Images
BRAND | FORM. | UNIT PRICE | PILL IMAGE |
---|---|---|---|
Potaba oral - | 500 mg capsule | ![]() |
Copyright © 2010 First DataBank, Inc.
Patient Handout
potassium aminobenzoate oral
POTASSIUM PARA-AMINOBENZOATE - ORAL
(poh-TASS-ee-um pair-uh-am-EE-no-BEN-zoh-ate)
COMMON BRAND NAME(S): Potaba
USES: This medication is used to treat certain skin disorders (such as dermatomyositis, scleroderma, Peyronie's disease). It helps make your skin more flexible and softens plaques. Potassium para-aminobenzoate is thought to work by increasing the use of oxygen in the skin.
HOW TO USE: Read the Patient Information Leaflet available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist.Take this medication by mouth with food as directed by your doctor, usually 4 to 6 times daily.If you are using the tablet form, first crush the prescribed number of tablets and dissolve in a full glass (8 ounces or 240 milliliters) of cold water or juice. Stir well and drink the entire mixture right away.If you are using capsules, take your prescribed dose with a full glass (8 ounces or 240 milliliters) of water, juice, or milk to lessen stomach upset.If you are using the powder in packet form, mix your dose in a full glass (8 ounces or 240 milliliters) of cold water or citrus juice. Stir well to dissolve, and drink the entire mixture right away. If you use water to prepare the mixture, you may also drink a citrus or carbonated beverage after taking each dose to wash away the taste of the medication.Dosage is based on your medical condition and response to treatment.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. It may take 2 months or more before you notice an improvement in symptoms.
SIDE EFFECTS: Upset stomach, nausea, or loss of appetite may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: signs of infection (such as sore throat that doesn't go away, fever).This medication can rarely cause low blood sugar (hypoglycemia). The risk for low blood sugar increases if you do not consume enough calories from food for several days. Symptoms include cold sweat, blurred vision, dizziness, drowsiness, shaking, fast heartbeat, headache, fainting, tingling of the hands/feet, and hunger. If these symptoms occur, rapidly raise your blood sugar by eating a quick source of sugar such as table sugar, honey, or candy, or drink fruit juice or non-diet soda. Tell your doctor about the reaction right away. To help prevent low blood sugar, eat meals on a regular schedule, and do not skip meals.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before taking potassium para-aminobenzoate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, low blood sugar (hypoglycemia), kidney disease.Older adults may be more sensitive to the side effects of this drug, especially low blood sugar. Tell your doctor right away if you have symptoms of low blood sugar, including confusion, headache, or trouble concentrating. (See also Side Effects section.)During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug are: aminosalicylates, sulfa drugs (such as sulfisoxazole).
OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
NOTES: Do not share this medication with others.Lab and/or medical tests (such as white blood cell counts) may be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.
MISSED DOSE: If you miss a dose, take it as soon as you remember unless it is less than 2 hours until the time of your next dose. In that case, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
STORAGE: Store the tablets, capsules, or unmixed powder between 46-59 degrees F (8-15 degrees C) away from light and moisture. If the powder form is not taken immediately after mixing, refrigerate the mixture in a container that is resistant to light (such as in an amber glass container, metal container, plastic container that you cannot see through). Do not freeze. Discard any unused mixture after 1 week. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised December 2022. Copyright(c) 2023 First Databank, Inc.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Formulary
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