aminobenzoate potassium (Rx)

Brand and Other Names:PABA, para aminobenzoic acid, more...Potaba
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Dosing & Uses

AdultPediatric

Dosing Strengths & Forms

capsule

  • 60mg
  • 500mg

tablet

  • 500mg

powder

  • 2g

Supplement

12 g PO divided q4-6hr

Administration

Take with adequate liquid to avoid gastric upset

Dosing Strengths & Forms

capsule

  • 60mg
  • 500mg

tablet

  • 500mg

powder

  • 2g

Supplement

1g/10 pounds of weight/day PO in divided doses

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Interactions

Interaction Checker

and aminobenzoate potassium

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (3)

              • sulfadiazine

                aminobenzoate potassium decreases effects of sulfadiazine by pharmacodynamic antagonism. Avoid or Use Alternate Drug.

              • sulfamethoxazole

                aminobenzoate potassium decreases effects of sulfamethoxazole by pharmacodynamic antagonism. Avoid or Use Alternate Drug.

              • sulfisoxazole

                aminobenzoate potassium decreases effects of sulfisoxazole by pharmacodynamic antagonism. Avoid or Use Alternate Drug.

              Monitor Closely (1)

              • omadacycline

                aminobenzoate potassium will decrease the level or effect of omadacycline by inhibition of GI absorption. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Separate dosing of tetracyclines from these products.

              Minor (0)

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                Adverse Effects

                Frequency Not Defined

                Anorexia

                Nausea

                Fever

                Hepatotoxicity

                Rash

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                Warnings

                Contraindications

                Hypersensitivity

                Concomitant sulfonamide antibiotics (effects may be nullified)

                Cautions

                Stop therapy if anorexia occurs and reinitiate therapy once appetite improves

                Stop therapy if nausea occurs and reinitiate therapy once patient improves

                Use wiht caution in diabetes mellitus, hypoglycemia, or renal disease

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                Pregnancy & Lactation

                Pregnancy Category: Not studied

                Lactation: Unknown if excreted in breast milk; use caution

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Mechanism of Action

                Related to B vitamins that may have antifibrotic effects by increasing oxygen uptake at tissues level

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                Images

                BRAND FORM. UNIT PRICE PILL IMAGE
                Potaba oral
                -
                500 mg capsule

                Copyright © 2010 First DataBank, Inc.

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                Patient Handout

                Patient Education
                potassium aminobenzoate oral

                POTASSIUM PARA-AMINOBENZOATE - ORAL

                (poh-TASS-ee-um pair-uh-am-EE-no-BEN-zoh-ate)

                COMMON BRAND NAME(S): Potaba

                USES: This medication is used to treat certain skin disorders (e.g., dermatomyositis, scleroderma, Peyronie's disease). It helps make your skin more flexible and softens plaques. Potassium para-aminobenzoate is thought to work by increasing the use of oxygen in the skin.

                HOW TO USE: Read the Patient Information Leaflet available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist.Take this medication by mouth with food, usually 4 to 6 times daily or as directed by your doctor.If you are using the tablet form, first crush the prescribed number of tablets and dissolve in a full glass (8 ounces or 240 milliliters) of cold water or juice. Stir well and drink the entire mixture right away.If you are using capsules, take your prescribed dose with a full glass (8 ounces or 240 milliliters) of water, juice, or milk to lessen stomach upset.If you are using the powder in packet form, mix your dose in a full glass (8 ounces or 240 milliliters) of cold water or citrus juice. Stir well to dissolve, and drink the entire mixture right away. If you use water to prepare the mixture, you may also drink a citrus or carbonated beverage after taking each dose to wash away the taste of the medication.Dosage is based on your medical condition and response to treatment.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. It may take 2 months or more before you notice an improvement in symptoms.

                SIDE EFFECTS: Upset stomach, nausea, or loss of appetite may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if any of these unlikely but serious side effects occur: signs of infection (e.g., persistent sore throat, fever).This medication can rarely cause low blood sugar (hypoglycemia). The risk for low blood sugar increases if you do not consume enough calories from food for several days. Symptoms include cold sweat, blurred vision, dizziness, drowsiness, shaking, fast heartbeat, headache, fainting, tingling of the hands/feet, and hunger. If these symptoms occur, rapidly raise your blood sugar by eating a quick source of sugar such as table sugar, honey, or candy, or drink fruit juice or non-diet soda. Tell your doctor about the reaction right away. To help prevent low blood sugar, eat meals on a regular schedule, and do not skip meals.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

                PRECAUTIONS: Before taking potassium para-aminobenzoate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, low blood sugar (hypoglycemia), kidney disease.The elderly may be more sensitive to the effects of this drug, especially low blood sugar. Tell your doctor right away if you have symptoms of low blood sugar, including confusion, headache, or trouble concentrating. (See also Side Effects section.)During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

                DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: aminosalicylates, sulfa drugs (e.g., sulfisoxazole).This document does not contain all possible interactions. Before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

                OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

                NOTES: Do not share this medication with others.Laboratory and/or medical tests (e.g., white blood cell counts) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

                MISSED DOSE: If you miss a dose, take it as soon as you remember unless it is less than 2 hours until the time of your next dose. In that case, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

                STORAGE: Store the tablets, capsules, or unmixed powder between 46-59 degrees F (8-15 degrees C) away from light and moisture. If the powder form is not taken immediately after mixing, refrigerate the mixture in a container that is resistant to light (such as in an amber glass container, metal container, plastic container that you cannot see through). Do not freeze. Discard any unused mixture after 1 week. Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

                Information last revised August 2021. Copyright(c) 2021 First Databank, Inc.

                IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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                Formulary

                FormularyPatient Discounts

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                • View the formulary and any restrictions for each plan.
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                The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

                Tier Description
                1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
                2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
                3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
                4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                NC NOT COVERED – Drugs that are not covered by the plan.
                Code Definition
                PA Prior Authorization
                Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
                QL Quantity Limits
                Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
                ST Step Therapy
                Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
                OR Other Restrictions
                Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.