pafolacianine (Pending FDA Approval)

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Dosing & Uses

Ovarian Cancer Imaging

Pending FDA approval as an adjunct in fluorescence-guided surgery for ovarian cancer

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Pharmacology

Mechanism of Action

Binds to folate receptors and illuminate intraoperatively under near-infrared light, serving as an adjunct to provide greater certainty during surgery of complete resection

Many cancers, including over 95% of ovarian cancer, over-express folate receptors to enable the uptake of folic acid

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.