Phosphatidylserine (Herb/Suppl)

Depression, mental impairment in geriatric, ADHD

Efficacy

Human trials show benefit in memory impairment, dementia

May lose its effectiveness with extended use > 16 weeks

Insufficient information for depression

Frequency Not Defined

None reported

Contraindications

N/A

Pregnancy Category: N/A

Lactation: N/A

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Major phospholipid in neuronal membranes

May increase acetylcholine release