phenylephrine/cocoa butter rectal (OTC)

Brand and Other Names:Preparation H Suppository
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

phenylephrine/cocoa butter

rectal ointment

  • 0.25%/88.44%

Hemorrhoids

Insert 1 suppository rectally

May apply up to 4 times/day, especially at night, in the morning, or after bowel movement that may exacerbate hemorrhoid(s)

Administration

Detach 1 suppository from the strip; remove the foil wrapper before inserting into the rectum as follows:

1) hold suppository with rounded end up

2) carefully separate foil tabs by inserting tip of fingernail at end marked "peel down"

3) slowly and evenly peel apart (do not tear) foil by pulling tabs down both sides, to expose the suppository

4) remove exposed suppository from wrapper

5) insert 1 suppository into the rectum up to 4 times daily, especially at night, in the morning or after each bowel movement

Dosage Forms & Strengths

phenylephrine/cocoa butter

rectal ointment

  • 0.25%/88.44%

Hemorrhoids

<12 years: Use is dependent on patient and if benefit outweighs risk

12 years or older: Insert 1 suppository rectally

May apply up to 4 times/day, especially at night, in the morning, or after bowel movement that may exacerbate hemorrhoid(s)

Administration

Detach 1 suppository from the strip; remove the foil wrapper before inserting into the rectum as follows:

1) hold suppository with rounded end up

2) carefully separate foil tabs by inserting tip of fingernail at end marked "peel down"

3) slowly and evenly peel apart (do not tear) foil by pulling tabs down both sides, to expose the suppository

4) remove exposed suppository from wrapper

5) insert 1 suppository into the rectum up to 4 times daily, especially at night, in the morning or after each bowel movement

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Adverse Effects

Frequency Not Defined

Allergic reaction

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Warnings

Contraindications

Hypersensitivity

Cautions

For rectal use only

Ask a healthcare professional if diagnosed with heart disease, high blood pressure, thyroid disease, diabetes, difficulty urination due to enlargement of prostate gland

Ask healthcare professional before use if presently taking a prescription drug for high blood pressure or depression

Do not exceed recommended daily dosage unless directed by a healthcare professional

Keep out of reach of children; if swallowed, get medical help or contact Poison Control Center immediately

Discontinue and contact physician if hemorrhoids worsen or do not improved within 7 days

Discontinue if bleeding, allergic reaction, redness, irritation, swelling, pain, or other symptoms develop or increase

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Pregnancy & Lactation

Pregnancy

Ask a healthcare professional

Lactation

Ask a healthcare professional

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Phenylephrine: Alpha adrenergic agonist; elicits localized vasoconstriction and decreases inflammation

Cocoa butter: Provides moisturizing and lubricating effects

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Images

BRAND FORM. UNIT PRICE PILL IMAGE
Preparation H (phenylephrine,cocoa butter) rectal
-
0.25-88.44 % suppos
Hemorrhoidal (phenylephrine-cocoa) rectal
-
0.25-88.44 % suppos

Copyright © 2010 First DataBank, Inc.

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Patient Handout

A Patient Handout is not currently available for this monograph.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.