Dosing & Uses
AdultPediatric
Dosage Forms & Strengths
nasal spray
- 0.05% (20mL)
Nasal Decongestant
1-2 sprays per nostril q6hr PRN
Dosage Forms & Strengths
nasal spray
- 0.05% (20mL)
Nasal Decongestant
< 12 years
- Not recommended
>12 years
- 1-2 sprays per nostril q6hr PRN
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Interactions
Interaction Checker
and naphazoline
No Results
No Interactions Found
Interactions Found
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
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Adverse Effects
Frequency Not Defined
CNS (anxiety, dizziness, tremor, etc)
Burning
Stinging
Sneezing
Dryness
Local irritation
Rebound congestion
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Warnings
Contraindications
Heart disease (incr BP, HR, palpitations)
Narrow angle glaucoma
Cautions
Caution in HTN, hyperthyroidism, ocular injury, DM, open-angle glaucoma
Overuse may cause rebound congestion
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Pregnancy & Lactation
Pregnancy Category: C
Lactation: not known if excreted in breast milk
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Previous
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Pharmacology
Mechanism of Action
Alpha 1 adrenergic agonist; stimulates alpha-adrenergic receptors in nasal conjunctiva and arterioles to produce vasoconstriction that results in nasal decongestion
Pharmacokinetics
Absorption: minimal systemic
Onset: 10 min
Duration: 2-6 hr
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Images
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Patient Handout
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
