hypotonic saline, intranasal (OTC)

Brand and Other Names:Rhinase Gel, Rhinase Mist
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

intranasal gel

  • Sodium chloride 0.22%
  • Potassium chloride 0.17%
  • Propylene glycol 15%
  • Polyethylene glycol 20%

intranasal mist

  • Sodium chloride 0.22%
  • Potassium chloride 0.17%
  • Propylene glycol 5%
  • Polyethylene glycol 15%

Nasal Dryness

Relieves dryness and irritation to and around the nose (nasal passages) caused by: dry room air, allergies, low humidity, chronic sinusitis, nose bleeds, stuffy nose, cold/flu, winter dryness, CPAP / BiPAP, travel, or oxygen therapy

Adds moisture inside the nose to dissolve and soften thick, crusty mucus, making it easier to remove

Mist: 1-2 sprays in each nostril q4hr or PRN

Gel: Apply gel around nostrils and under nose as often as needed; may be placed in nostrils to help relieve discomfort

Dosage Forms & Strengths

intranasal gel

  • Sodium chloride 0.22%
  • Potassium chloride 0.17%
  • Propylene glycol 15%
  • Polyethylene glycol 20%

intranasal mist

  • Sodium chloride 0.22%
  • Potassium chloride 0.17%
  • Propylene glycol 5%
  • Polyethylene glycol 15%

Nasal Dryness

Relieves dryness and irritation to and around the nose (nasal passages) caused by: dry room air, allergies, low humidity, chronic sinusitis, nose bleeds, stuffy nose, cold/flu, winter dryness, CPAP / BiPAP, travel, or oxygen therapy

Adds moisture inside the nose to dissolve and soften thick, crusty mucus, making it easier to remove

<2 years: Safety and efficacy not established

≥2 years

  • Mist: 1-2 sprays in each nostril q4hr or PRN
  • Gel: Apply gel around nostrils and under nose as often as needed; may be placed in nostrils to help relieve discomfort
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Adverse Effects

None listed

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Warnings

Contraindications

None

Cautions

Keep out of reach of children

Not for ingestion

Avoid contact with eyes

Use of same tube/spray by >1 person may spread infection

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Pregnancy & Lactation

Pregnancy

No known risk

Lactation

No known risk

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Nasal cavity moisturizer

NaCl and KCl amounts creates a hypotonic saline that works with the body’s own Na+/K+ pump to moisturize the nasal cavity

The propylene and PEG wetting agents ensure efficient distribution of the product and the salts

Unique compared with other intranasal salines; the hypotonic pH of 6.2 is the same as corticosteroid sprays and the normal pH of the nasal cavity; therefore, there is less stinging, less interference with adsorption of intranasal steroids, and it maintains the slightly acidic pH of the nose

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Administration

Storage

Store between 30°C

Protect from freezing

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Images

No images available for this drug.
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Patient Handout

A Patient Handout is not currently available for this monograph.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.