eflapegrastim (Pending FDA Approval)

Brand and Other Names:Rolontis
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Dosing & Uses

Chemotherapy-Induced Neutropenia

Pending FDA approval for treatment of chemotherapy-induced neutropenia

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Pharmacology

Mechanism of Action

Recombinant granulocyte-colony stimulating factor (G-CSF) analog; acts on hematopoietic cells by binding to specific cell surface receptors, thereby stimulating proliferation, differentiation, commitment, and end-cell functional activation

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.