Rose Hips (Herb/Suppl)

Brand and Other Names:rosa canina
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Suggested Dosing

Supplement

500-750 mg/d, preferably with meals

Tea

Steep 2-2.5 grams of the crushed rose hips in 150 mL boiling water for 10-15 min, then strain liquid before ingesting

No limits are placed on amounts of rose hip tea that may be consumed per day

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Suggested Uses

Rich source of Vitamin C, with about 1700-2000 mg per 100 g in dried product

Remedy for rheumatoid arthritis

Reduces symptoms of knee & hip osteoarthritis

Helps the immune system to fight off foreign invaders & out of control cells

Facilitates fat metabolism

Protects tissues from free radical damage

Assists the nervous system by converting certain amino acids into neurotransmitters

Prevents scurvy

Protects joints and connective tissues

Protects adrenal function

Ability to prevent urinary bladder infections, & assist in treating dizziness & headaches

Used externally in oil form to restore firmness to skin by nourishing & astringing tissue

Brewed into a decoction, can also be used to treat constipation

Rose hips contain lots of iron, rose hip tea is used during menstruation to make up for iron loss

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Interactions

Interaction Checker

and Rose Hips

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              Serious - Use Alternative (12)

              • demeclocycline

                rose hips decreases levels of demeclocycline by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              • doxycycline

                rose hips decreases levels of doxycycline by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              • eltrombopag

                rose hips decreases levels of eltrombopag by inhibition of GI absorption. Applies only to oral form of both agents. Contraindicated. Separate by at least 4 hours.

              • fleroxacin

                rose hips decreases levels of fleroxacin by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              • gemifloxacin

                rose hips decreases levels of gemifloxacin by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              • levofloxacin

                rose hips decreases levels of levofloxacin by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              • minocycline

                rose hips decreases levels of minocycline by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              • moxifloxacin

                rose hips decreases levels of moxifloxacin by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              • mycophenolate

                rose hips decreases levels of mycophenolate by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Interaction only with oral iron administration.

              • ofloxacin

                rose hips decreases levels of ofloxacin by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              • oxytetracycline

                rose hips decreases levels of oxytetracycline by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              • tetracycline

                rose hips decreases levels of tetracycline by inhibition of GI absorption. Applies only to oral form of both agents. Avoid or Use Alternate Drug.

              Monitor Closely (36)

              • aluminum hydroxide

                aluminum hydroxide will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • amoxicillin

                amoxicillin, rose hips. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor.

              • ampicillin

                ampicillin, rose hips. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor.

              • calcium carbonate

                calcium carbonate will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • cimetidine

                cimetidine will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • deferoxamine

                deferoxamine, rose hips. Other (see comment). Use Caution/Monitor. Comment: Ascorbic acid increases the availability of iron for chelation with deferoxamine. Ascorbic acid should be avoided in pts. with cardiac failure undergoing deferoxamine Tx. Clinical cardiac monitoring recommended for pts. supplemented with ascorbic acid.

                deferoxamine decreases levels of rose hips by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor. Deferoxamine chelates iron.

              • dexlansoprazole

                dexlansoprazole will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • enalapril

                enalapril, rose hips. Mechanism: unknown. Use Caution/Monitor. Risk of GI symptoms, hypotension.

              • esomeprazole

                esomeprazole will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • famotidine

                famotidine will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • ibandronate

                rose hips decreases levels of ibandronate by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.

              • ibuprofen/famotidine

                ibuprofen/famotidine will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • lansoprazole

                lansoprazole will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • levothyroxine

                rose hips decreases levels of levothyroxine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.

              • liothyronine

                rose hips decreases levels of liothyronine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.

              • methotrexate

                rose hips will increase the level or effect of methotrexate by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor.

              • methyldopa

                rose hips decreases levels of methyldopa by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.

              • mycophenolate

                rose hips will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor.

              • nafcillin

                nafcillin, rose hips. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor.

              • nizatidine

                nizatidine will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • omeprazole

                omeprazole will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • oxacillin

                oxacillin, rose hips. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor.

              • pantoprazole

                pantoprazole will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • penicillamine

                rose hips decreases levels of penicillamine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor. Interaction only with oral iron administration.

              • penicillin G aqueous

                penicillin G aqueous, rose hips. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor.

              • penicillin VK

                penicillin VK, rose hips. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor.

              • pivmecillinam

                pivmecillinam, rose hips. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor.

              • probenecid

                rose hips will increase the level or effect of probenecid by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor.

              • rabeprazole

                rabeprazole will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • sodium bicarbonate

                sodium bicarbonate will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • sodium citrate/citric acid

                sodium citrate/citric acid will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Use Caution/Monitor.

              • temocillin

                temocillin, rose hips. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor.

              • thyroid desiccated

                rose hips decreases levels of thyroid desiccated by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.

              • ticarcillin

                ticarcillin, rose hips. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor.

              • trientine

                trientine, rose hips. Either decreases levels of the other by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor. Separate by 2 hr.

              • wheat germ extract

                rose hips decreases effects of wheat germ extract by unknown mechanism. Use Caution/Monitor. Mfr. recommends separating by 2 hrs.

              Minor (109)

              • aceclofenac

                rose hips will increase the level or effect of aceclofenac by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • acemetacin

                rose hips will increase the level or effect of acemetacin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • acetohydroxamic acid

                acetohydroxamic acid decreases levels of rose hips by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • acyclovir

                rose hips will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • aluminum hydroxide

                rose hips increases levels of aluminum hydroxide by enhancing GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • aminohippurate sodium

                rose hips will increase the level or effect of aminohippurate sodium by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • amobarbital

                amobarbital decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • ascorbic acid

                ascorbic acid will increase the level or effect of rose hips by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • aspirin

                rose hips will increase the level or effect of aspirin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                aspirin decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips increases levels of aspirin by decreasing renal clearance. Minor/Significance Unknown.

              • aspirin rectal

                rose hips will increase the level or effect of aspirin rectal by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                rose hips increases levels of aspirin rectal by decreasing renal clearance. Minor/Significance Unknown.

                aspirin rectal decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

              • aspirin/citric acid/sodium bicarbonate

                aspirin/citric acid/sodium bicarbonate decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips will increase the level or effect of aspirin/citric acid/sodium bicarbonate by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                rose hips increases levels of aspirin/citric acid/sodium bicarbonate by decreasing renal clearance. Minor/Significance Unknown.

              • balsalazide

                rose hips will increase the level or effect of balsalazide by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                balsalazide decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips increases levels of balsalazide by decreasing renal clearance. Minor/Significance Unknown.

              • bazedoxifene/conjugated estrogens

                bazedoxifene/conjugated estrogens decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • bendroflumethiazide

                rose hips will increase the level or effect of bendroflumethiazide by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • butabarbital

                butabarbital decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • butalbital

                butalbital decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • calcium acetate

                calcium acetate decreases levels of rose hips by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

                rose hips increases levels of calcium acetate by enhancing GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • calcium carbonate

                calcium carbonate decreases levels of rose hips by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

                rose hips increases levels of calcium carbonate by enhancing GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • calcium chloride

                calcium chloride decreases levels of rose hips by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

                rose hips increases levels of calcium chloride by enhancing GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • calcium citrate

                calcium citrate decreases levels of rose hips by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

                rose hips increases levels of calcium citrate by enhancing GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • calcium gluconate

                calcium gluconate decreases levels of rose hips by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

                rose hips increases levels of calcium gluconate by enhancing GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • cefaclor

                rose hips will increase the level or effect of cefaclor by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefadroxil

                rose hips will increase the level or effect of cefadroxil by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefamandole

                rose hips will increase the level or effect of cefamandole by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefazolin

                rose hips will increase the level or effect of cefazolin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefdinir

                rose hips will increase the level or effect of cefdinir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefditoren

                rose hips will increase the level or effect of cefditoren by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefepime

                rose hips will increase the level or effect of cefepime by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefixime

                rose hips will increase the level or effect of cefixime by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefotaxime

                rose hips will increase the level or effect of cefotaxime by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefotetan

                rose hips will increase the level or effect of cefotetan by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefoxitin

                rose hips will increase the level or effect of cefoxitin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefpirome

                rose hips will increase the level or effect of cefpirome by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefpodoxime

                rose hips will increase the level or effect of cefpodoxime by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefprozil

                rose hips will increase the level or effect of cefprozil by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • ceftazidime

                rose hips will increase the level or effect of ceftazidime by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • ceftibuten

                rose hips will increase the level or effect of ceftibuten by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • ceftriaxone

                rose hips will increase the level or effect of ceftriaxone by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cefuroxime

                rose hips will increase the level or effect of cefuroxime by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • celecoxib

                rose hips will increase the level or effect of celecoxib by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • cephalexin

                rose hips will increase the level or effect of cephalexin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • chlorothiazide

                rose hips will increase the level or effect of chlorothiazide by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • chlorpropamide

                rose hips will increase the level or effect of chlorpropamide by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • chlorthalidone

                rose hips will increase the level or effect of chlorthalidone by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • choline magnesium trisalicylate

                choline magnesium trisalicylate decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips will increase the level or effect of choline magnesium trisalicylate by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                rose hips increases levels of choline magnesium trisalicylate by decreasing renal clearance. Minor/Significance Unknown.

              • chromium

                rose hips increases levels of chromium by enhancing GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • conjugated estrogens

                conjugated estrogens decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • conjugated estrogens, vaginal

                conjugated estrogens, vaginal decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • copper

                rose hips decreases levels of copper by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • cyanocobalamin

                rose hips decreases levels of cyanocobalamin by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • cyclopenthiazide

                rose hips will increase the level or effect of cyclopenthiazide by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • demeclocycline

                demeclocycline decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • diclofenac

                rose hips will increase the level or effect of diclofenac by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • didanosine

                didanosine will decrease the level or effect of rose hips by increasing gastric pH. Applies only to oral form of both agents. Minor/Significance Unknown.

              • diflunisal

                rose hips will increase the level or effect of diflunisal by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                diflunisal decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips increases levels of diflunisal by decreasing renal clearance. Minor/Significance Unknown.

              • doxycycline

                doxycycline decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • estradiol

                estradiol decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • estrogens conjugated synthetic

                estrogens conjugated synthetic decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • estrogens esterified

                estrogens esterified decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • estropipate

                estropipate decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • etodolac

                rose hips will increase the level or effect of etodolac by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • fenbufen

                rose hips will increase the level or effect of fenbufen by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • fenoprofen

                rose hips will increase the level or effect of fenoprofen by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • flurbiprofen

                rose hips will increase the level or effect of flurbiprofen by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • ganciclovir

                rose hips will increase the level or effect of ganciclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • gymnema

                gymnema decreases levels of rose hips by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • hydrochlorothiazide

                rose hips will increase the level or effect of hydrochlorothiazide by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • ibuprofen

                rose hips will increase the level or effect of ibuprofen by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • ibuprofen IV

                rose hips will increase the level or effect of ibuprofen IV by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • indapamide

                rose hips will increase the level or effect of indapamide by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • indomethacin

                rose hips will increase the level or effect of indomethacin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • ketoprofen

                rose hips will increase the level or effect of ketoprofen by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • ketorolac

                rose hips will increase the level or effect of ketorolac by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • ketorolac intranasal

                rose hips will increase the level or effect of ketorolac intranasal by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • levocarnitine

                rose hips decreases levels of levocarnitine by unspecified interaction mechanism. Minor/Significance Unknown.

              • lornoxicam

                rose hips will increase the level or effect of lornoxicam by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • manganese

                rose hips decreases levels of manganese by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • meclofenamate

                rose hips will increase the level or effect of meclofenamate by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • mefenamic acid

                rose hips will increase the level or effect of mefenamic acid by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • meloxicam

                rose hips will increase the level or effect of meloxicam by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • mesalamine

                rose hips will increase the level or effect of mesalamine by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                mesalamine decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips increases levels of mesalamine by decreasing renal clearance. Minor/Significance Unknown.

              • mestranol

                mestranol decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • methyclothiazide

                rose hips will increase the level or effect of methyclothiazide by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • metolazone

                rose hips will increase the level or effect of metolazone by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • minocycline

                minocycline decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • nabumetone

                rose hips will increase the level or effect of nabumetone by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • naproxen

                rose hips will increase the level or effect of naproxen by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • nicotine inhaled

                nicotine inhaled decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • nicotine intranasal

                nicotine intranasal decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • oxaprozin

                rose hips will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • oxytetracycline

                oxytetracycline decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • parecoxib

                rose hips will increase the level or effect of parecoxib by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • pentobarbital

                pentobarbital decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • phenobarbital

                phenobarbital decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • piperacillin

                rose hips will increase the level or effect of piperacillin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • piroxicam

                rose hips will increase the level or effect of piroxicam by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • primidone

                primidone decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • salicylates (non-asa)

                rose hips will increase the level or effect of salicylates (non-asa) by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                salicylates (non-asa) decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips increases levels of salicylates (non-asa) by decreasing renal clearance. Minor/Significance Unknown.

              • salsalate

                rose hips will increase the level or effect of salsalate by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                salsalate decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips increases levels of salsalate by decreasing renal clearance. Minor/Significance Unknown.

              • secobarbital

                secobarbital decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • sulfasalazine

                rose hips will increase the level or effect of sulfasalazine by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                sulfasalazine decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips increases levels of sulfasalazine by decreasing renal clearance. Minor/Significance Unknown.

              • sulindac

                rose hips will increase the level or effect of sulindac by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • tetracycline

                tetracycline decreases levels of rose hips by increasing elimination. Minor/Significance Unknown.

              • tolfenamic acid

                rose hips will increase the level or effect of tolfenamic acid by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • tolmetin

                rose hips will increase the level or effect of tolmetin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • valganciclovir

                rose hips will increase the level or effect of valganciclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

              • vitamin E

                vitamin E decreases levels of rose hips by inhibition of GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown.

              • warfarin

                rose hips decreases effects of warfarin by pharmacodynamic antagonism. Minor/Significance Unknown. Dose >10 g/day vitamin C.

              • willow bark

                rose hips will increase the level or effect of willow bark by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown.

                willow bark decreases levels of rose hips by increasing renal clearance. Minor/Significance Unknown.

                rose hips increases levels of willow bark by decreasing renal clearance. Minor/Significance Unknown.

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              Adverse Effects

              Frequency Not Defined

              Kidney stones

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              Warnings

              Contraindications

              Sickle cell anemia

              Cautions

              Headache

              Heartburn

              Insomnia

              Nausea

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              Pregnancy & Lactation

              Pregnancy Category: unknown

              Lactation: safe

              Pregnancy Categories

              A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

              B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

              C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

              D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

              X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

              NA: Information not available.

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              Pharmacology

              Metabolism: N/A

              Excretion: N/A

              Mechanism of Action

              Antioxidant, unique water-soluble nutrient able to scavenge certain types of free radicals before they have a chance to damage lipids and other cellular components

              Shown to work along side of vitamin E, a fat-soluble antioxidant, and the enzyme glutathione peroxidase to stop the free radical chain reactions from getting out of hand

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              Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.