roxadustat (Pending FDA Approval)

Brand and Other Names:
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Dosing & Uses

Anemia of Chronic Kidney Disease

Pending FDA approval for treatment of anemia of chronic kidney disease in both non-dialysis-dependent and dialysis-dependent patients

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Pharmacology

Mechanism of Action

Hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI); promotes coordinated erythropoiesis through increasing endogenous erythropoietin, improving iron availability, and reducing hepcidin

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Patient Handout

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.