Dosing & Uses
COVID-19 Treatment
Pending FDA Emergency Use Authorization for treatment of hospitalized patients with COVID-19 at high risk for acute respiratory distress syndrome (ARDS)
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Pharmacology
Mechanism of Action
Elicits dual anti-inflammatory and antiviral by disrupting microtubule filaments
Binds alpha and beta tubulin to inhibit tubulin polymerization
Inhibition of tubulin polymerization effects cell migration, cytokine release, intracellular trafficking (antiviral), and disruption of inflammatory cell activities
Microtubule trafficking is critical for viruses, such as SARS CoV-2, to cause infection
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Images
No images available for this drug.
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
