Dosing & Uses
Dosage Forms & Strengths
tablet
- 50mcg
- 100mcg
- 125mcg
- 200mcg
tablet extended release
- 200mcg
capsule
- 200mcg
injectable solution
- 40mcg/mL
RDA
Male or female: 55 mcg/day
Pregnancy: 60 mcg/day
Lactating: 70 mcg/day
Supplementation
100-200 mcg/day PO with meals (preferably); may take 50 mcg PO qDay or q6hr
Dosage Forms & Strengths
tablet
- 50mcg
- 100mcg
- 125mcg
- 200mcg
tablet extended release
- 200mcg
capsule
- 200mcg
injectable solution
- 40mcg/mL
RDA
<6 months: 15 mcg/day
6-12 months: 20 mcg/day
1-3 years: 20 mcg/day
4-8 years: 30 mcg/day
8-13 years: 40 mcg/day
13-18 years: 55 mcg/day
Interactions
Interaction Checker
No Results

Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor

Contraindicated (0)
Serious - Use Alternative (2)
- baloxavir marboxil
selenium will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Avoid or Use Alternate Drug. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. Human studies not conducted.
- eltrombopag
selenium decreases levels of eltrombopag by inhibition of GI absorption. Applies only to oral form of both agents. Contraindicated. Separate by at least 4 hours.
Monitor Closely (13)
- alendronate
selenium will decrease the level or effect of alendronate by cation binding in GI tract. Modify Therapy/Monitor Closely. Avoid administering polyvalent cations 2 hr before or 30 min after alendronate.
- bictegravir
selenium will decrease the level or effect of bictegravir by cation binding in GI tract. Modify Therapy/Monitor Closely. Administer bictegravir on an empty stomach at least 2 h before or 6 h after polyvalent cation containing drugs.
- deferiprone
selenium will decrease the level or effect of deferiprone by cation binding in GI tract. Modify Therapy/Monitor Closely. Separate deferiprone administration from ingestion of polyvalent cations by at least 4 h.
- dolutegravir
selenium will decrease the level or effect of dolutegravir by cation binding in GI tract. Modify Therapy/Monitor Closely. Administer dolutegravir at least 2 h before or 6 h after polyvalent cations. Administer the dolutegravir/rilpivirine combination at least 4 h before or 6 h after polyvalent cations.
- eltrombopag
selenium will decrease the level or effect of eltrombopag by cation binding in GI tract. Modify Therapy/Monitor Closely. Separate eltrombopag administration from polyvalent cations by at least 2 h.
- etidronate
selenium will decrease the level or effect of etidronate by cation binding in GI tract. Modify Therapy/Monitor Closely. Avoid administering polyvalent cations 2 hr before or after etidronate.
- ibandronate
selenium will decrease the level or effect of ibandronate by cation binding in GI tract. Modify Therapy/Monitor Closely. Avoid administering polyvalent cations 2 hr before or 1 h after ibandronate.
- omadacycline
selenium will decrease the level or effect of omadacycline by cation binding in GI tract. Modify Therapy/Monitor Closely. Do not take polyvalent cations within 4 hr before or after omadacycline.
- penicillamine
selenium will decrease the level or effect of penicillamine by cation binding in GI tract. Modify Therapy/Monitor Closely. Separate penicillamine administration from ingestion of polyvalent cations by at least 1 h.
- raltegravir
selenium will decrease the level or effect of raltegravir by cation binding in GI tract. Modify Therapy/Monitor Closely. Administer raltegravir at least 2 h before or 6 h after polyvalent cations. Note: Dose separation may not adequately avoid this interaction.
- risedronate
selenium will decrease the level or effect of risedronate by cation binding in GI tract. Modify Therapy/Monitor Closely. Avoid administering polyvalent cations 2 hr before or 30 min after risedronate.
- tiludronate
selenium will decrease the level or effect of tiludronate by cation binding in GI tract. Modify Therapy/Monitor Closely. Avoid administering polyvalent cations 2 hr before or after tiludronate.
- trientine
selenium will decrease the level or effect of trientine by cation binding in GI tract. Modify Therapy/Monitor Closely. Administer trientine at least 1 hr before or after polyvalent cations (2 hr if oral iron administered).
Minor (0)
Adverse Effects
Frequency Not Defined
Irritability
Warnings
Contraindications
Hypersensitivity
Undiluted injection into peripheral vein
Cautions
Inform all of your health care providers that you take selenium supplement, including doctors, nurses, pharmacists, and dentists
Have blood work checked as advised by healthcare professional
Inform healthcare professional if pregnant, plan on getting pregnant, or are breast-feeding; talk about benefits and risks to mother and baby
Pregnancy & Lactation
Pregnancy
Selenium is found in placenta and cord blood; teratogenic effects not reported with nontoxic doses
Lactation
Selenium is found in breast milk; adverse effects not reported with nontoxic maternal doses
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Antioxidant; cofactor in glutathione peroxidase; protects cell components from oxidative damage
Present in selenoproteins as selenocysteine amino acid residue
Pharmacokinetics
Excretion: Urine, feces, lungs, skin
Images
BRAND | FORM. | UNIT PRICE | PILL IMAGE |
---|---|---|---|
selenium intravenous - | 40 mcg/mL vial | ![]() | |
Selenious Acid intravenous - | 60 mcg/mL vial | ![]() | |
Selenious Acid intravenous - | 60 mcg/mL vial | ![]() | |
selenium oral - | 200 mcg tablet | ![]() | |
selenium oral - | 200 mcg capsule | ![]() |
Copyright © 2010 First DataBank, Inc.
Patient Handout
selenium intravenous
NO MONOGRAPH AVAILABLE AT THIS TIME
USES: Consult your pharmacist.
HOW TO USE: Consult your pharmacist.
SIDE EFFECTS: Consult your pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Consult your pharmacist.
DRUG INTERACTIONS: Consult your pharmacist.Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
NOTES: No monograph available at this time.
MISSED DOSE: Consult your pharmacist.
STORAGE: Consult your pharmacist.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised July 2016. Copyright(c) 2023 First Databank, Inc.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.