senna/psyllium (OTC)

Brand and Other Names:Senna Prompt
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

senna/psyllium

capsule

  • 9mg/500mg

Constipation

5 capsules PO qDay or q12hr

Dosage Forms & Strengths

senna/psyllium

capsule

  • 9mg/500mg

Constipation

<12 years: Safety & efficacy not established

≥12 years: 5 capsules PO qDay or q12hr

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Interactions

Interaction Checker

and senna/psyllium

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     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Electrolyte imbalance

            Potassium loss

            Abdominal cramping

            Excessive bowel activity

            Flatulence

            Yellow-brown urine discoloration

            Melanosis coli

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            Warnings

            Contraindications

            Hypersensitivity

            GI obstruction or perforation

            Ulcerative colitis

            Symptoms of appendicitis or acute surgical abdomen

            Fecal impaction

            GI bleeding

            Rectal bleeding

            Cautions

            Use caution in patients with esophageal strictures, stenosis, ulcers, difficulty swallowing, or intestinal adhesions

            May predispose the elderly to fecal impaction and bowel obstruction if fluid intake is low

            Product must be taken with at least 8 ounces of fluid to prevent choking

            Not recommended in patients experiencing stomach pain

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            Pregnancy & Lactation

            Pregnancy category: C (senna); B psyllium

            Lactation: Use caution

            Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

            Pregnancy Categories

            A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA: Information not available.

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            Pharmacology

            Mechanism of Action

            Senna: Intestinal irritant/stimulant

            Psyllium: Bulk-producing laxative

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            Images

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            Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.