Dosing & Uses
Dosage Forms & Strengths
senna/psyllium
capsule
- 9mg/500mg
Constipation
5 capsules PO qDay or q12hr
Dosage Forms & Strengths
senna/psyllium
capsule
- 9mg/500mg
Constipation
<12 years: Safety & efficacy not established
≥12 years: 5 capsules PO qDay or q12hr
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Adverse Effects
Frequency Not Defined
Electrolyte imbalance
Potassium loss
Abdominal cramping
Excessive bowel activity
Flatulence
Yellow-brown urine discoloration
Melanosis coli
Warnings
Contraindications
Hypersensitivity
GI obstruction or perforation
Ulcerative colitis
Symptoms of appendicitis or acute surgical abdomen
Fecal impaction
GI bleeding
Rectal bleeding
Cautions
Use caution in patients with esophageal strictures, stenosis, ulcers, difficulty swallowing, or intestinal adhesions
May predispose the elderly to fecal impaction and bowel obstruction if fluid intake is low
Product must be taken with at least 8 ounces of fluid to prevent choking
Not recommended in patients experiencing stomach pain
Pregnancy & Lactation
Pregnancy category: C (senna); B psyllium
Lactation: Use caution
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Senna: Intestinal irritant/stimulant
Psyllium: Bulk-producing laxative
