Dosing & Uses
Dietary Supplement
5-20 mg/day, maximum 50 mg/day; up to 700 mg taken without apparent harm
Daily diet normally provides enough to meet requirements
Sources of silicon: Oats, rice, and barley; also found in fruits and vegetables
Efficacy: Insufficient data
Safety & efficacy not established
Adverse Effects
None known; silicon present in neurofibrillary tangles in Alzheimer's disease
Warnings
Contraindications
Hypersensitivity
Pregnancy & Lactation
Pregnancy Category: N/A
Lactation: N/A
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Implicated in gene transcription of type I collagen gene, a cofactor for prolyl hydroxylase the enzyme involved in collagen synthesis; may be associated with keeping bones and connective tissues healthy
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Formulary
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all your plans together – even plans in different states.
- Compare formulary status to other drugs in the same class.
- Access your plan list on any device – mobile or desktop.