Dosing & Uses
Dosage Forms & Strengths
topical solution
- 0.5%
- 10%
- 25%
- 50%
applicator sticks
silver nitrate/potassium nitrate
-
75%/25%
Antiseptic Wound Cauterization
Sticks: Apply to mucous membranes and other moist skin surfaces only on area to be treated
Topical solution: Apply a cotton applicator dipped in solution/ointment on the affected area 2-3 times per week for 2-3 weeks
Supralumbar Kertaconjunctivitis (Off-label)
Apply 0.5-1% solution to anesthetized upper tarsus, allow it to fall back into place over affected palpebral conjunctiva
Irrigate with sterile saline after 1 minute
May be repeated after 4-6 weeks
Dosage Forms & Strengths
topical solution
- 0.5%
- 10%
- 25%
- 50%
applicator sticks
silver nitrate/potassium nitrate
-
75%/25%
Antiseptic Wound Cauterization
Sticks: Apply to mucous membranes and other moist skin surfaces only on area to be treated
Topical solution: Apply a cotton applicator dipped in solution/ointment on the affected area 2-3 times per week for 2-3 weeks
Interactions
Interaction Checker
No Results

Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor

Contraindicated (0)
Serious - Use Alternative (1)
- allogeneic cultured keratinocytes and fibroblasts
silver nitrate decreases effects of allogeneic cultured keratinocytes and fibroblasts by Other (see comment). Avoid or Use Alternate Drug. Comment: Silver-containing antimicrobials and dressings may decrease viability of keratinocytes and human dermal fibroblasts.
Monitor Closely (5)
- collagenase
silver nitrate decreases effects of collagenase by Other (see comment). Use Caution/Monitor. Comment: Heavy metal ions inactivate enzymes.
- papain
silver nitrate decreases effects of papain by Other (see comment). Use Caution/Monitor. Comment: Heavy metal ions inactivate enzymes.
- sodium sulfacetamide
silver nitrate decreases effects of sodium sulfacetamide by Other (see comment). Use Caution/Monitor. Comment: Topical preparations are physically incompatible.
- sulfacetamide topical
silver nitrate decreases effects of sulfacetamide topical by Other (see comment). Use Caution/Monitor. Comment: Topical preparations are physically incompatible.
- trypsin
silver nitrate decreases effects of trypsin by Other (see comment). Use Caution/Monitor. Comment: Heavy metal ions inactivate enzymes.
Minor (0)
Adverse Effects
Frequency Not Defined
Burning and skin irritation
Staining of the skin
Methemoglobinemia
Warnings
Contraindications
Hypersensitivity
Broken skin, wounds, or cuts
Cautions
Highly toxic to gastrointestinal tract and central nervous system when ingested; swallowing can cause sever gastroenteritis that may be fatal; may perform gastric lavage with sodium chloride to remove chemical
Avoid prolonged contact with skin or other surfaces since staining may occur
Solution is caustic and irritating to skin and mucous membrane
Do not irrigate eye after application of 1% solution
Chemical burns may result from inapropriate use of product
Skin contact time with applicators should be minimal when used in thin delicate skin or neonates
Must be handled carefully; tends to stain skin, utensils, clothing, and linens
Pregnancy & Lactation
Pregnancy
Ask a healthcare professional
Lactation
Ask a healthcare professional
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Antiseptic that denatures proteins, acts on surface of bacteria causing substantial changes in cell wall and membrane
Images
BRAND | FORM. | UNIT PRICE | PILL IMAGE |
---|---|---|---|
silver nitrate topical - | 0.5 % solution | ![]() | |
silver nitrate topical - | 10 % solution | ![]() | |
silver nitrate topical - | 50 % solution | ![]() | |
silver nitrate topical - | 25 % solution | ![]() |
Copyright © 2010 First DataBank, Inc.
Patient Handout
silver nitrate topical
NO MONOGRAPH AVAILABLE AT THIS TIME
USES: Consult your pharmacist.
HOW TO USE: Consult your pharmacist.
SIDE EFFECTS: Consult your pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Consult your pharmacist.
DRUG INTERACTIONS: Consult your pharmacist.Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
NOTES: No monograph available at this time.
MISSED DOSE: Consult your pharmacist.
STORAGE: Consult your pharmacist.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised July 2016. Copyright(c) 2023 First Databank, Inc.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Formulary
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