silver nitrate (Rx)

Brand and Other Names:
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

topical solution

  • 0.5%
  • 10%
  • 25%
  • 50%

applicator sticks

  • 75%

Antiseptic Wound Cauterization

Sticks: Apply to mucous membranes and other moist skin surfaces only on area to be treated

Topical solution: Apply a cotton applicator dipped in solution/ointment on the affected area 2-3 times per week for 2-3 weeks

Supralumbar Kertaconjunctivitis (Off-label)

Apply 0.5-1% solution to anesthetized upper tarsus, allow it to fall back into place over affected palpebral conjunctiva

Irrigate with sterile saline after 1 minute

May be repeated after 4-6 weeks

Dosage Forms & Strengths

topical solution

  • 0.5%
  • 10%
  • 25%
  • 50%

applicator sticks

  • 75%

Antiseptic Wound Cauterization

Sticks: Apply to mucous membranes and other moist skin surfaces only on area to be treated

Topical solution: Apply a cotton applicator dipped in solution/ointment on the affected area 2-3 times per week for 2-3 weeks

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Interactions

Interaction Checker

and silver nitrate

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (1)

              • allogeneic cultured keratinocytes and fibroblasts

                silver nitrate decreases effects of allogeneic cultured keratinocytes and fibroblasts by Other (see comment). Avoid or Use Alternate Drug. Comment: Silver-containing antimicrobials and dressings may decrease viability of keratinocytes and human dermal fibroblasts.

              Monitor Closely (5)

              • collagenase

                silver nitrate decreases effects of collagenase by Other (see comment). Use Caution/Monitor. Comment: Heavy metal ions inactivate enzymes.

              • papain

                silver nitrate decreases effects of papain by Other (see comment). Use Caution/Monitor. Comment: Heavy metal ions inactivate enzymes.

              • sodium sulfacetamide

                silver nitrate decreases effects of sodium sulfacetamide by Other (see comment). Use Caution/Monitor. Comment: Topical preparations are physically incompatible.

              • sulfacetamide topical

                silver nitrate decreases effects of sulfacetamide topical by Other (see comment). Use Caution/Monitor. Comment: Topical preparations are physically incompatible.

              • trypsin

                silver nitrate decreases effects of trypsin by Other (see comment). Use Caution/Monitor. Comment: Heavy metal ions inactivate enzymes.

              Minor (0)

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                Adverse Effects

                Frequency Not Defined

                Burning and skin irritation

                Staining of the skin

                Methemoglobinemia

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                Warnings

                Contraindications

                Hypersensitivity

                Broken skin, wounds, or cuts

                Cautions

                Avoid prolonged contact with skin or other surfaces since staining may occur

                May irritate skin & mucous membranes

                Do not irrigate eye after application of 1% solution

                Chemical burns may result from inapropriate use of product

                Skin contact time with applicators should be minimal when used in thin delicate skin or neonates

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                Pregnancy & Lactation

                Pregnancy Category: C

                Lactation: Not studied

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

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                Pharmacology

                Mechanism of Action

                Antiseptic that denatures proteins, acts on surface of bacteria causing substantial changes in cell wall and membrane

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                Images

                BRAND FORM. UNIT PRICE PILL IMAGE
                silver nitrate topical
                -
                0.5 % solution
                silver nitrate topical
                -
                50 % solution
                silver nitrate topical
                -
                25 % solution
                silver nitrate topical
                -
                10 % solution

                Copyright © 2010 First DataBank, Inc.

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                Patient Handout

                Patient Education
                silver nitrate topical

                NO MONOGRAPH AVAILABLE AT THIS TIME

                USES: Consult your pharmacist.

                HOW TO USE: Consult your pharmacist.

                SIDE EFFECTS: Consult your pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

                PRECAUTIONS: Consult your pharmacist.

                DRUG INTERACTIONS: Consult your pharmacist.Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

                OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

                NOTES: No monograph available at this time.

                MISSED DOSE: Consult your pharmacist.

                STORAGE: Consult your pharmacist.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

                Information last revised July 2016. Copyright(c) 2021 First Databank, Inc.

                IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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                Formulary

                FormularyPatient Discounts

                Adding plans allows you to compare formulary status to other drugs in the same class.

                To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

                Adding plans allows you to:

                • View the formulary and any restrictions for each plan.
                • Manage and view all your plans together – even plans in different states.
                • Compare formulary status to other drugs in the same class.
                • Access your plan list on any device – mobile or desktop.

                The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

                Tier Description
                1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
                2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
                3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
                4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                NC NOT COVERED – Drugs that are not covered by the plan.
                Code Definition
                PA Prior Authorization
                Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
                QL Quantity Limits
                Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
                ST Step Therapy
                Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
                OR Other Restrictions
                Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.