sodium chloride hypertonic, ophthalmic (OTC)

Brand and Other Names:Muro 128 2%, Muro 128 5%, more...Muro 128 5% Ointment
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Sections

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ophthalmic solution

  • 2%
  • 5%

ophthalmic ointment

  • 5%

Temporary Relief of Corneal Edema

Ophthalmic solution: Instill 1-2 gtt in affected eye(s) q3-4h or as directed by physician

Ophthalmic ointment: Pull down lower lid of affected eye(s); apply a small amount (1/4 inch) of ointment to inside of eyelid; apply once daily or as directed by physician

Administration

Ophthalmic ointment recommended for nighttime use; preservative free formulation

Ophthalmic solution recommended for daytime use

Avoid contamination do not touch tip of container to any surface; replace cap after use

Dosage Forms & Strengths

opthalmic solution

  • 2%
  • 5%

ophthalmic ointment

  • 5%

Temporary Relief of Corneal Edema

Ophthalmic solution: Instill 1-2 drops in affected eye(s) q3-4h or as directed by physician

Ophthalmic ointment: Pull down lower lid of affected eye(s); apply a small amount (1/4 inch) of ointment to inside of eyelid; apply q3-4h or as directed by physician

Administration

Ophthalmic ointment recommended for nighttime use; preservative free formulation

Ophthalmic solution recommended for daytime use

Avoid contamination do not touch tip of container to any surface; replace cap after use

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Adverse Effects

Frequency Not Defined

May cause temporary burning and irritation

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Warnings

Contraindications

Hypersensitivity to any component of the product

Cautions

Do not use if solution changes color or becomes cloudy

If condition worsens or persists for more than 72 hours or if you experience eye pain, changes in vision, continued redness or irritation of the eye consult a physician

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Pregnancy & Lactation

Pregnant or breastfeeding patients should seek advice of health care provider before using OTC drugs

Lactation: Consult a health care provider before using in breast-feeding women.

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Reduces corneal edema and associated symptoms by osmotic pressure control; draws excess fluid from cornea into tears

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Images

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.