Dosing & Uses
Dosage Forms & Strengths
infusion solution
- 5 mEq/mL (560 mg/mL)
Alkalinizing Agent
As directed by physician (based on severity of metabolic acidosis)
Dosage Forms & Strengths
infusion solution
- 500mL
- 1000mL
Alkalinizing Agent
As directed by physician (based on severity of metabolic acidosis)
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Contraindicated (0)
Serious - Use Alternative (0)
Monitor Closely (9)
- bearberry
sodium lactate will increase the level or effect of bearberry by passive renal tubular reabsorption - basic urine. Use Caution/Monitor.
- benzphetamine
sodium lactate will increase the level or effect of benzphetamine by passive renal tubular reabsorption - basic urine. Use Caution/Monitor.
- dextroamphetamine
sodium lactate will increase the level or effect of dextroamphetamine by passive renal tubular reabsorption - basic urine. Use Caution/Monitor.
- ephedrine
sodium lactate will increase the level or effect of ephedrine by passive renal tubular reabsorption - basic urine. Use Caution/Monitor.
- flecainide
sodium lactate will increase the level or effect of flecainide by passive renal tubular reabsorption - basic urine. Use Caution/Monitor.
- memantine
sodium lactate will increase the level or effect of memantine by passive renal tubular reabsorption - basic urine. Use Caution/Monitor.
- mexiletine
sodium lactate will increase the level or effect of mexiletine by passive renal tubular reabsorption - basic urine. Use Caution/Monitor.
- pseudoephedrine
sodium lactate will increase the level or effect of pseudoephedrine by passive renal tubular reabsorption - basic urine. Use Caution/Monitor.
- quinidine
sodium lactate will increase the level or effect of quinidine by passive renal tubular reabsorption - basic urine. Use Caution/Monitor.
Minor (0)
Adverse Effects
Frequency Not Defined
Febrile response
Injection site infections
Phlebitis
Thrombosis
Extravasation
Hypervolemia
Warnings
Contraindications
Not for lactic acidosis
Hypernatremia or fluid retention
CHF, shock, respiratory alkalosis or other conditions that increase lactate
Cautions
Significant hypokalemia may occur
No advantage over sodium bicarbonate and is contraindicated in the treatment of lactic acidosis
Avoid rapid administration and overdosage
Excess administration may result in metabolic alkalosis
Severe renal impairment, edema with sodium retention
Not for correcting severe acidotic states
Pregnancy & Lactation
Pregnancy Category: C
Lactation: use caution
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Lactate is converted into bicarbonate
Pharmacokinetics
Metabolism: lactate is converted in the liver into bicarbonate
Administration
IV Administration
NMT 300 mL/hr in adults
Do not use plastic containers in series connections
Use only non-vented set or vented set with vent closed
IV Incompatibilities
Additive: Na-bicarbonate
Storage
Store at 40°C or less
Protect from extreme heat & freezing
Images
Formulary
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Adding plans allows you to:
- View the formulary and any restrictions for each plan.
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- Compare formulary status to other drugs in the same class.
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