stannsoporfin (Pending FDA Approval)

Brand and Other Names:

Dosing & Uses

AdultPediatric

See Pediatric Dosing

Hyperbilirubinemia

Pending FDA approval to reduce bilirubin production in neonates at risk for severe neonatal jaundice

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Pharmacology

Mechanism of Action

Heme oxygenase inhibitor; blocks the conversion of heme into bilirubin

Heme is converted to biliverdin by heme oxygenase, and then biliverdin is converted to bilirubin by biliverdin reductase

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.