Dosing & Uses
AdultPediatric
See Pediatric Dosing
Hyperbilirubinemia
Pending FDA approval to reduce bilirubin production in neonates at risk for severe neonatal jaundice
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Pharmacology
Mechanism of Action
Heme oxygenase inhibitor; blocks the conversion of heme into bilirubin
Heme is converted to biliverdin by heme oxygenase, and then biliverdin is converted to bilirubin by biliverdin reductase
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
