Indication-specific dosing for stevia rebaudiana (stevia), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Sections

Sections Stevia
Suggested Dosing
Suggested Uses
Interactions
Adverse Effects
Warnings
Pregnancy
Pharmacology

Suggested Dosing

Hypertension

250-500 mg PO TID

Hyperglycemia

1 g stevioside take with meals

Water extracts of 5 g of leaves q 6hr x 3 days to increase glucose tolerance

Suggested Uses

Non-caloric sweetener for foods/beverages

Hyperglycemia, weight loss aid, diuretic, & hypertension

Efficacy

Studies inconclusive and contradictory

Interaction Checker

Enter a drug name and Stevia

No Results

No Interactions Found

Interactions Found

Contraindicated

Serious - Use Alternative

Significant - Monitor Closely

Minor

All Interactions Sort By:

Contraindicated (0)

Serious - Use Alternative (0)

Monitor Closely (0)

Minor (18)

acarbose
stevia increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.
chlorpropamide
stevia increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.
glimepiride
stevia increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.
glipizide
stevia increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.
glyburide
stevia increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.
insulin degludec
stevia increases effects of insulin degludec by pharmacodynamic synergism. Minor/Significance Unknown.
insulin degludec/insulin aspart
stevia increases effects of insulin degludec/insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.
metformin
stevia increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.
miglitol
stevia increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.
nateglinide
stevia increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.
pioglitazone
stevia increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
repaglinide
stevia increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.
rosiglitazone
stevia increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
saxagliptin
stevia increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
sitagliptin
stevia increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
tolazamide
stevia increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.
tolbutamide
stevia increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.
vildagliptin
stevia increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

acarbose
Minor (1)stevia increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.
chlorpropamide
Minor (1)stevia increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.
glimepiride
Minor (1)stevia increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.
glipizide
Minor (1)stevia increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.
glyburide
Minor (1)stevia increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.
insulin degludec
Minor (1)stevia increases effects of insulin degludec by pharmacodynamic synergism. Minor/Significance Unknown.
insulin degludec/insulin aspart
Minor (1)stevia increases effects of insulin degludec/insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.
metformin
Minor (1)stevia increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.
miglitol
Minor (1)stevia increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.
nateglinide
Minor (1)stevia increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.
pioglitazone
Minor (1)stevia increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
repaglinide
Minor (1)stevia increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.
rosiglitazone
Minor (1)stevia increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
saxagliptin
Minor (1)stevia increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
sitagliptin
Minor (1)stevia increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
tolazamide
Minor (1)stevia increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.
tolbutamide
Minor (1)stevia increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.
vildagliptin
Minor (1)stevia increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

Adverse Effects

Allergic reaction

Contraindications

Hypersensitivity to Asteraceae family (ragweed, daisies, etc)

Cautions

FDA, WHO, European regulatory agencies have questioned safety of chronic use

Pregnancy & Lactation

Pregnancy Category: N/A

Lactation: N/A

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Stevioside 100x sweeter than sucrose

Stevioside, steviol may decr GI absorption of glucose and stimulate insulin secretion

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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