Suggested Dosing
Hypertension
250-500 mg PO TID
Hyperglycemia
1 g stevioside take with meals
Water extracts of 5 g of leaves q 6hr x 3 days to increase glucose tolerance
Suggested Uses
Non-caloric sweetener for foods/beverages
Hyperglycemia, weight loss aid, diuretic, & hypertension
Efficacy
Studies inconclusive and contradictory
Interactions
Interaction Checker
No Results
Contraindicated
Serious - Use Alternative
Significant - Monitor Closely
Minor
Contraindicated (0)
Serious - Use Alternative (0)
Monitor Closely (0)
Minor (18)
- acarbose
stevia increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.
- chlorpropamide
stevia increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.
- glimepiride
stevia increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.
- glipizide
stevia increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.
- glyburide
stevia increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.
- insulin degludec
stevia increases effects of insulin degludec by pharmacodynamic synergism. Minor/Significance Unknown.
- insulin degludec/insulin aspart
stevia increases effects of insulin degludec/insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.
- metformin
stevia increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.
- miglitol
stevia increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.
- nateglinide
stevia increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.
- pioglitazone
stevia increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
- repaglinide
stevia increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.
- rosiglitazone
stevia increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.
- saxagliptin
stevia increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
- sitagliptin
stevia increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
- tolazamide
stevia increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.
- tolbutamide
stevia increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.
- vildagliptin
stevia increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.
Adverse Effects
Allergic reaction
Warnings
Contraindications
Hypersensitivity to Asteraceae family (ragweed, daisies, etc)
Cautions
FDA, WHO, European regulatory agencies have questioned safety of chronic use
Pregnancy & Lactation
Pregnancy Category: N/A
Lactation: N/A
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Stevioside 100x sweeter than sucrose
Stevioside, steviol may decr GI absorption of glucose and stimulate insulin secretion
