Stevia (Herb/Suppl)

Brand and Other Names:stevia rebaudiana
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Suggested Dosing

Hypertension

250-500 mg PO TID

Hyperglycemia

1 g stevioside take with meals

Water extracts of 5 g of leaves q 6hr x 3 days to increase glucose tolerance

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Suggested Uses

Non-caloric sweetener for foods/beverages

Hyperglycemia, weight loss aid, diuretic, & hypertension

Efficacy

Studies inconclusive and contradictory

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Interactions

Interaction Checker

and Stevia

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (0)

                Monitor Closely (0)

                  Minor (18)

                  • acarbose

                    stevia increases effects of acarbose by pharmacodynamic synergism. Minor/Significance Unknown.

                  • chlorpropamide

                    stevia increases effects of chlorpropamide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • glimepiride

                    stevia increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown.

                  • glipizide

                    stevia increases effects of glipizide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • glyburide

                    stevia increases effects of glyburide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • insulin degludec

                    stevia increases effects of insulin degludec by pharmacodynamic synergism. Minor/Significance Unknown.

                  • insulin degludec/insulin aspart

                    stevia increases effects of insulin degludec/insulin aspart by pharmacodynamic synergism. Minor/Significance Unknown.

                  • metformin

                    stevia increases effects of metformin by pharmacodynamic synergism. Minor/Significance Unknown.

                  • miglitol

                    stevia increases effects of miglitol by pharmacodynamic synergism. Minor/Significance Unknown.

                  • nateglinide

                    stevia increases effects of nateglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • pioglitazone

                    stevia increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • repaglinide

                    stevia increases effects of repaglinide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • rosiglitazone

                    stevia increases effects of rosiglitazone by pharmacodynamic synergism. Minor/Significance Unknown.

                  • saxagliptin

                    stevia increases effects of saxagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                  • sitagliptin

                    stevia increases effects of sitagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

                  • tolazamide

                    stevia increases effects of tolazamide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • tolbutamide

                    stevia increases effects of tolbutamide by pharmacodynamic synergism. Minor/Significance Unknown.

                  • vildagliptin

                    stevia increases effects of vildagliptin by pharmacodynamic synergism. Minor/Significance Unknown.

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                  Adverse Effects

                  Allergic reaction

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                  Warnings

                  Contraindications

                  Hypersensitivity to Asteraceae family (ragweed, daisies, etc)

                  Cautions

                  FDA, WHO, European regulatory agencies have questioned safety of chronic use

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                  Pregnancy & Lactation

                  Pregnancy Category: N/A

                  Lactation: N/A

                  Pregnancy Categories

                  A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                  B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                  C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                  D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                  X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                  NA: Information not available.

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                  Pharmacology

                  Metabolism: N/A

                  Excretion: N/A

                  Mechanism of Action

                  Stevioside 100x sweeter than sucrose

                  Stevioside, steviol may decr GI absorption of glucose and stimulate insulin secretion

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                  Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.