Dosing & Uses
Pancreatic Cancer
Investigational/Orphan Status
Intratumoral injections
Other Information
Intratumoral injection for pancreatic cancer guided by endoscopic ultrasound
Other Indications & Uses
Investigational: head & neck cancer, esophageal cancer, rectal cancer
Safety & efficacy not established
Adverse Effects
Frequency Not Defined
Data limited, unknown
Warnings
Data limited, unknown
Pregnancy & Lactation
Pregnancy Category: unknown, avoid pregnancy
Lactation: Unknown if excreted in breast milk, do not breast feed
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
Adenovector (DNA carrier) that contains the gene for tumor necrosis factor-alpha (TNF-alpha), an immune system protein with potent and well-documented anticancer effects
Images
Formulary
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all your plans together – even plans in different states.
- Compare formulary status to other drugs in the same class.
- Access your plan list on any device – mobile or desktop.